Simple Summary The deregulation of the oxidative metabolism in cancer cells,
characterized by an increased ratio between glycolysis and oxygen consumption (Warburgv …

Endothelial cells play an obligatory role in regulating local vascular tone and maintaining
homeostasis in vascular biology. Cell metabolism, converting food to energy in organisms, is …

A role for hypoxia‐inducible factors (HIFs) in hypoxia‐dependent regulation of tumor cell
metabolism has been thoroughly investigated and covered in reviews. However, there is …

Mitochondria are major energy-producing organelles that have central roles in cellular
metabolism. They also act as important signalling hubs, and their dynamic regulation in …

Rationale: Specific mechanisms linking inflammation and metabolic reprogramming—two
hallmarks of many pathobiological processes—remain incompletely defined. Objective: To …

The mitochondrial pyruvate carrier (MPC) is the entry point for the glycolytic end-product
pyruvate to the mitochondria. MPC activity, which is controlled by its abundance and post …

Aims Mitochondrial dysfunction is a critical pathological change in cerebral ischemia.
Mitochondrial pyruvate carrier 1 (MPC1) is a mitochondrial inner membrane protein carrier …

The discovery void of antimicrobial development has occurred at a time when the world has
seen a rapid emergence and spread of antimicrobial resistance, the 'perfect storm'as it has …

Expansion of bone marrow-derived endothelial progenitor cells (EPCs) in vitro to obtain
required cell numbers for therapeutic applications faces the challenge of growing cell …

Endothelial cell (EC) metabolism has emerged as a driver of angiogenesis. While hypoxia
inactivates the oxygen sensors prolyl-4 hydroxylase domain-containing proteins 1–3 (PHD1 …