Clinical trials with mesenchymal stem cells: an update

T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …

Animal models of spinal cord injury: a systematic review

M Sharif-Alhoseini, M Khormali, M Rezaei, M Safdarian… - Spinal cord, 2017 - nature.com
Study Design: PRISMA-guided systematic review. Objectives: To provide a comprehensive
framework of the current animal models for investigating spinal cord injury (SCI) and …

3D bioprinted neural tissue constructs for spinal cord injury repair

X Liu, M Hao, Z Chen, T Zhang, J Huang, J Dai… - Biomaterials, 2021 - Elsevier
Abstract Three-dimensional (3D) bioprinting has emerged as a promising approach to
fabricate living neural constructs with anatomically accurate complex geometries and spatial …

Polymer scaffolds facilitate spinal cord injury repair

Q Zhang, B Shi, J Ding, L Yan, JP Thawani, C Fu… - Acta biomaterialia, 2019 - Elsevier
During the past decades, improving patient neurological recovery following spinal cord
injury (SCI) has remained a challenge. An effective treatment for SCI would not only reduce …

Natural-based biomaterials for peripheral nerve injury repair

BE Fornasari, G Carta, G Gambarotta… - … in bioengineering and …, 2020 - frontiersin.org
Peripheral nerve injury treatment is a relevant problem because of nerve lesion high
incidence and because of unsatisfactory regeneration after severe injuries, thus resulting in …

Injectable hydrogel materials for spinal cord regeneration: a review

D Macaya, M Spector - Biomedical materials, 2012 - iopscience.iop.org
Spinal cord injury (SCI) presents a complex regenerative problem due to the multiple facets
of growth inhibition that occur following trauma to the cord parenchyma and stroma …

A systematic review of animal models used to study nerve regeneration in tissue-engineered scaffolds

D Angius, H Wang, RJ Spinner, Y Gutierrez-Cotto… - Biomaterials, 2012 - Elsevier
Research on biomaterial nerve scaffolds has been carried out for 50 years. Only three
materials (collagen, polycaprolactone and polyglycollic acid) have progressed to clinical …

Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds

NN Madigan, S McMahon, T O'Brien… - Respiratory physiology …, 2009 - Elsevier
This review highlights current tissue engineering and novel therapeutic approaches to
axonal regeneration following spinal cord injury. The concept of developing 3-dimensional …

Human embryonic stem cell-derived neural stem cells encapsulated in hyaluronic acid promotes regeneration in a contusion spinal cord injured rat

M Zarei-Kheirabadi, H Sadrosadat… - International journal of …, 2020 - Elsevier
Abstract spinal cord injury (SCI) is a traumatic damage that can causes a loss of neurons
around the lesion site and resulting in locomotor and sensory deficits. Currently, there is …

Melanin incorporated electroactive and antioxidant silk fibroin nanofibrous scaffolds for nerve tissue engineering

M Nune, S Manchineella, T Govindaraju… - Materials Science and …, 2019 - Elsevier
Nerve restoration and repair in the central nervous system is complicated and requires
several factors to be considered while designing the scaffolds like being bioactive as well as …