Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
pulmonary injury or multiple-organ injury by various pathological pathways. Transforming …

Cardiovascular disease (CVD) continues to be the primary cause of global mortality.
Vascular smooth muscle cells (VSMCs) are integral components of vascular structure and …

Objective Arsenic trioxide (ATO or As 2 O 3) has beneficial effects on suppressing neointimal
hyperplasia and restenosis, but the mechanism is still unclear. The goal of this study is to …

Endothelial cells in blood vessels in the kidney exert different functions depending on the
(micro) vascular bed they are located in. The present study aimed to investigate microRNA …

Background Many microRNAs (miRNAs) have been associated with asthma and chronic
obstructive pulmonary disease (COPD). Longitudinal lung function growth trajectories of …

For more than 100 years, the human amniotic membrane (hAM) has been used in multiple
tissue regeneration applications. The hAM consists of cells with stem cell characteristics and …

It has been shown that mesenchymal stromal cells (MSC)-based tissue engineering has
potential clinical application because of its paracrine effect, differentiation ability and high …

The esophagus exhibits peristalsis via contraction of circularly and longitudinally aligned
smooth muscles, and esophageal replacement is required if there is a critical-sized wound …

Background Aging is one of the dominant factors contributing to erectile dysfunction (ED),
and effective treatments for age-associated ED are urgently demanded. In this study, the …

Senescence is a form of durable cell cycle arrest elicited in response to a wide range of
stimuli. Senescent cells remain metabolically active and secrete a variety of factors …