Neurological involvement in HIV is often associated with cognitive impairment. Although
severe and progressive neurocognitive impairment has become rare in HIV clinics in the era …

Cross-sectional studies show that around half of individuals infected with HIV-1 have some
degree of cognitive impairment despite the use of antiretroviral drugs. However, prevalence …

Apolipoprotein E (ApoE) is a multifunctional protein critical for lipid metabolism and
cholesterol homeostasis. In addition to being a well-known genetic determinant of both …

Human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND) affects
roughly half the HIV-positive population. The symptoms of cognitive slowing, poor …

Marked improvements in survival and health outcome for people infected with HIV have
occurred since the advent of combination antiretroviral therapy over a decade ago. Yet HIV …

Alzheimer's disease (AD) is a highly heritable disease (with heritability up to 76%) with a
complex genetic profile of susceptibility, among which large genome-wide association …

HIV-associated neurocognitive disorder : Current Opinion in Infectious Diseases HIV-associated
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Microglia support productive human immunodeficiency virus type 1 (HIV‐1) infection and
disturbed microglial function could contribute to the development of HIV‐associated …

Currently, neuropsychological impairment among HIV+ patients on antiretroviral therapy
leads to a reduction in the quality of life and it is an important challenge due to the high …

HIV-associated neurocognitive disorders (HAND) continue to affect a large proportion of
persons living with HIV despite effective viral suppression with combined antiretroviral …