Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches

A Safavi, A Kefayat, E Mahdevar, A Abiri… - Vaccine, 2020 - Elsevier
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …

[PDF][PDF] Immunogenicity prediction by VaxiJen: a ten year overview

N Zaharieva, I Dimitrov, D Flower… - J. Proteom …, 2017 - ddg-pharmfac.net
Vaccination stands alone as an unparalleled medical intervention able to save human lives
numbering hundreds of millions. Modern licensed vaccines are either whole organism …

Major histocompatibility complex linked databases and prediction tools for designing vaccines

SP Singh, BN Mishra - Human immunology, 2016 - Elsevier
Presently, the major histocompatibility complex (MHC) is receiving considerable interest
owing to its remarkable role in antigen presentation and vaccine design. The specific …

Revisiting the dimensions of universal vaccine with special focus on COVID-19: Efficacy versus methods of designing

P Jaishwal, K Jha, SP Singh - International Journal of Biological …, 2024 - Elsevier
Even though the use of SARS-CoV-2 vaccines during the COVID-19 pandemic showed
unprecedented success in a short time, it also exposed a flaw in the current vaccine design …

Post-Genomics and Vaccine Improvement for Leishmania

N Seyed, T Taheri, S Rafati - Frontiers in microbiology, 2016 - frontiersin.org
Leishmaniasis is a parasitic disease that primarily affects Asia, Africa, South America, and
the Mediterranean basin. Despite extensive efforts to develop an effective prophylactic …

Vaccinomics Approach for Designing Potential Peptide Vaccine by Targeting Shigella spp. Serine Protease Autotransporter Subfamily Protein SigA

AR Oany, T Pervin, M Mia, M Hossain… - Journal of …, 2017 - Wiley Online Library
Shigellosis, a bacillary dysentery, is closely associated with diarrhoea in human and causes
infection of 165 million people worldwide per year. Casein‐degrading serine protease …

Genome based screening of epitope ensemble vaccine candidates against dreadful visceral leishmaniasis using immunoinformatics approach

G Singh, M Pritam, M Banerjee, AK Singh… - Microbial …, 2019 - Elsevier
Visceral leishmaniasis (VL) is a dreadful protozoan disease caused by Leishmania
donovani that severely affects huge populations in tropical and sub-tropical regions. The …

Immunoinformatics based design and prediction of proteome-wide killer cell epitopes of Leishmania donovani: Potential application in vaccine development

M Kashif, SK Hira, PP Manna - Journal of Biomolecular Structure …, 2022 - Taylor & Francis
Despite several extensive and exhaustive efforts, search for potential therapy against
leishmaniasis has not made much progress. In the present work, we have employed mining …

A structural vaccinology approach for in silico designing of a potential self-assembled nanovaccine against Leishmania infantum

B Vakili, N Nezafat, M Negahdaripour… - Experimental …, 2022 - Elsevier
Visceral leishmaniasis (VL) remains a major public health problem across 98 countries. To
date, VL has no effective drug. Vaccines, as the most successful breakthroughs in medicine …

Designing of precise vaccine construct against visceral leishmaniasis through predicted epitope ensemble: a contemporary approach

G Singh, M Pritam, M Banerjee, AK Singh… - … biology and chemistry, 2020 - Elsevier
Visceral leishmaniasis (VL) caused by Leishmania donovani is a fatal parasitic disease
affecting primarily the poor population in endemic countries. Increasing number of deaths as …