[HTML][HTML] Advances in the early diagnosis of hepatocellular carcinoma

W Wang, C Wei - Genes & diseases, 2020 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most prevalent cancers globally. In contrast to
the declining death rates observed for all other common cancers such as breast, lung, and …

Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA

Q Ye, S Ling, S Zheng, X Xu - Molecular cancer, 2019 - Springer
Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of
death worldwide. Due to latent liver disease, late diagnosis, and nonresponse to systemic …

Biomarkers for diagnosis and therapeutic options in hepatocellular carcinoma

YT Chan, C Zhang, J Wu, P Lu, L Xu, H Yuan, Y Feng… - Molecular Cancer, 2024 - Springer
Liver cancer is a global health challenge, causing a significant social-economic burden.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …

Utility of liquid biopsy analysis in detection of hepatocellular carcinoma, determination of prognosis, and disease monitoring: a systematic review

VL Chen, D Xu, MS Wicha, AS Lok… - Clinical Gastroenterology …, 2020 - Elsevier
Background & Aims Liquid biopsies, or blood samples, can be analyzed to detect circulating
tumor cells (CTCs), cell-free DNA (cfDNA), and extracellular vesicles, which might identify …

[HTML][HTML] DNA methylation-driven genes for constructing diagnostic, prognostic, and recurrence models for hepatocellular carcinoma

J Long, P Chen, J Lin, Y Bai, X Yang, J Bian, Y Lin… - Theranostics, 2019 - ncbi.nlm.nih.gov
In this study, we performed a comprehensively analysis of gene expression and DNA
methylation data to establish diagnostic, prognostic, and recurrence models for …

Clinical applications of liquid biopsy as prognostic and predictive biomarkers in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA

J Li, X Han, X Yu, Z Xu, G Yang, B Liu, P Xiu - Journal of Experimental & …, 2018 - Springer
Hepatocellular carcinoma (HCC) is a highly malignant disease with a poor prognosis and
high mortality due to a low early diagnosis rate, resistance to systemic treatments and …

[HTML][HTML] Liquid biopsy in patients with hepatocellular carcinoma: Circulating tumor cells and cell-free nucleic acids

W Okajima, S Komatsu, D Ichikawa… - World Journal of …, 2017 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC), with its high incidence and mortality rate, is one of the
most common malignant tumors. Despite recent development of a diagnostic and treatment …

[HTML][HTML] Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma

C Zhang, J Li, T Huang, S Duan, D Dai, D Jiang, X Sui… - Oncotarget, 2016 - ncbi.nlm.nih.gov
DNA methylation is an epigenetic mechanism in the pathogenesis of hepatocellular
carcinoma (HCC). Here, we conducted a systematic meta-analysis to evaluate the …

Frizzled7 as an emerging target for cancer therapy

TD King, W Zhang, MJ Suto, Y Li - Cellular signalling, 2012 - Elsevier
Wnt proteins are secreted glycoproteins that bind to the N-terminal extra-cellular cysteine-
rich domain of the Frizzled (Fzd) receptor family. The Fzd receptors can respond to Wnt …

[HTML][HTML] Using cell-free DNA for HCC surveillance and prognosis

NH Tran, J Kisiel, LR Roberts - JHEP Reports, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer. Its
incidence is rising faster than any other cancer in the United States and it remains one of the …