FGF4 retrogene on CFA12 is responsible for chondrodystrophy and intervertebral disc disease in dogs

EA Brown, PJ Dickinson, T Mansour… - Proceedings of the …, 2017 - National Acad Sciences
Chondrodystrophy in dogs is defined by dysplastic, shortened long bones and premature
degeneration and calcification of intervertebral discs. Independent genome-wide …

[图书][B] Breed predispositions to disease in dogs and cats

A Gough, A Thomas, D O'Neill - 2018 - books.google.com
Breed Predispositions to Disease in Dogs and Cats, Third Edition provides a comprehensive
exploration of current knowledge of breed predispositions based on rigorous examination of …

Magnetic resonance imaging in dogs with neurologic impairment due to acute thoracic and lumbar intervertebral disk herniation

JM Levine, GT Fosgate, AV Chen… - Journal of veterinary …, 2009 - Wiley Online Library
Background: Magnetic resonance imaging (MRI) is a correlate to physical examination in
various myelopathies and a predictor of functional outcome. Objectives: To describe …

Comparison between noncontrast computed tomography and magnetic resonance imaging for detection and characterization of thoracolumbar myelopathy caused by …

JJ Cooper, BD Young, JF Griffin IV… - Veterinary Radiology …, 2014 - Wiley Online Library
Magnetic resonance imaging (MRI) and computed tomography (CT) are commonly used to
evaluate dogs with thoracolumbar myelopathy; however, relative diagnostic sensitivities for …

The relative sensitivity of computed tomography and myelography for identification of thoracolumbar intervertebral disk herniations in dogs

SK Israel, JM Levine, SC Kerwin… - Veterinary radiology …, 2009 - Wiley Online Library
We compared the relative sensitivity of computed tomography (CT) and myelography for
identification of disk herniation in dogs. Criteria for patient selection included presurgical CT …

Clinical and magnetic resonance imaging features of canine compressive cervical myelopathy with suspected hydrated nucleus pulposus extrusion

E Beltran, R Dennis, V Doyle… - Journal of Small …, 2012 - Wiley Online Library
Objective: To describe clinical and magnetic resonance imaging features in dogs with
compressive cervical myelopathy due to acute suspected hydrated nucleus pulposus …

Canine chondrodysplasia caused by a truncating mutation in collagen-binding integrin alpha subunit 10

K Kyöstilä, AK Lappalainen, H Lohi - PloS one, 2013 - journals.plos.org
The skeletal dysplasias are disorders of the bone and cartilage tissues. Similarly to humans,
several dog breeds have been reported to suffer from different types of genetic skeletal …

Dog as a model for osteoarthritis: the fgf4 retrogene insertion may matter

AR Tellegen, AJ Dessing, K Houben… - Journal of …, 2019 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease associated with chronic pain and
disability in humans and companion animals. The canine species can be subdivided into …

Cerebrospinal fluid myelin basic protein as a prognostic biomarker in dogs with thoracolumbar intervertebral disk herniation

GJ Levine, JM Levine, TH Witsberger… - Journal of veterinary …, 2010 - Wiley Online Library
Background: Release of myelin basic protein (MBP) into the cerebrospinal fluid (CSF) is
associated with active demyelination and correlates with outcome in various neurological …

Relationships between cerebrospinal fluid characteristics, injury severity, and functional outcome in dogs with and without intervertebral disk herniation

GJ Levine, JR Cook, SC Kerwin… - Veterinary Clinical …, 2014 - Wiley Online Library
Background Cerebrospinal fluid (CSF) is commonly acquired in dogs with intervertebral disk
herniation (IVDH) and is a common method to assess inflammatory responses following …