Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …

Redox processes are at the heart of synthetic methods that rely on either electrochemistry or
photoredox catalysis, but how do electrochemistry and photoredox catalysis compare? Both …

Light‐driven homogeneous and heterogeneous catalysis require a complex interplay
between light absorption, charge separation, charge transfer, and catalytic turnover. Optical …

We report an organophotocatalytic, N–CH3-selective oxidation of trialkylamines in
continuous flow. Based on the 9, 10-dicyanoanthracene (DCA) core, a new catalyst (DCAS) …

N-Demethylation of trialkylamines is a useful transformation, but typically requires harsh
reaction conditions and stepwise procedures, as well as judicious protection of labile …

This chapter provides a short overview of the history of morphine since it's isolation by
Sertürner in 1805. The biosynthesis of the title alkaloid as well as all total and formal …

This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

N-dealkylation, the removal of an N-alkyl group from an amine, is an important chemical
transformation which provides routes for the synthesis of a wide range of pharmaceuticals …

Photochemical activation using red or near-infrared light has recently emerged as a
potential remedy for solving fundamental issues in photochemistry such as selectivity and …

The most challenging step in the preparation of many opioid antagonists is the selective N-
demethylation of a 14-hydroxymorphinan precursor. This process is carried out on a large …