Siderophores: an alternative bioremediation strategy?

Z Roskova, R Skarohlid, L McGachy - Science of the Total Environment, 2022 - Elsevier
Siderophores are small molecular weight iron scavengers that are mainly produced by
bacteria, fungi, and plants. Recently, they have attracted increasing attention because of …

Metal binding ability of microbial natural metal chelators and potential applications

M Hofmann, G Retamal-Morales, D Tischler - Natural Product Reports, 2020 - pubs.rsc.org
Covering: up to 2019 Siderophores are natural products which have attracted interest due to
their ability to bind metal ions with high affinities. This review considers the complex …

Native mass spectrometry-based metabolomics identifies metal-binding compounds

AT Aron, D Petras, R Schmid, JM Gauglitz, I Büttel… - Nature …, 2022 - nature.com
Although metals are essential for the molecular machineries of life, systematic methods for
discovering metal–small molecule complexes from biological samples are limited. Here, we …

[HTML][HTML] Promising Antifungal Targets Against Candida albicans Based on Ion Homeostasis

Y Li, L Sun, C Lu, Y Gong, M Li, S Sun - Frontiers in cellular and …, 2018 - frontiersin.org
In recent decades, invasive fungal infections have been increasing significantly, contributing
to high incidences and mortality in immunosuppressed patients. Candida albicans (C …

Semenogelins Armed in Zn(II) and Cu(II): May Bioinorganic Chemistry Help Nature to Cope with Enterococcus faecalis?

D Dudek, A Miller, A Hecel, A Kola, D Valensin… - Inorganic …, 2023 - ACS Publications
Proteolytic degradation of semenogelins, the most abundant proteins from human semen,
results in the formation of 26-and 29-amino acid peptides (SgIIA and SgI-29, respectively) …

Candida albicans

D Wilson - Trends in Microbiology, 2019 - cell.com
Pathogens often face zinc restriction due to the action of nutritional immunity–host processes
which restrict microbial access to key micronutrients such as zinc and iron. Candida albicans …

Transcription factors and transporters in zinc homeostasis: lessons learned from fungi

DJ Eide - Critical reviews in biochemistry and molecular biology, 2020 - Taylor & Francis
Zinc is an essential nutrient for all organisms because this metal serves as a critical
structural or catalytic cofactor for many proteins. These zinc-dependent proteins are …

[HTML][HTML] Candida and Complement: New Aspects in an Old Battle

V Harpf, G Rambach, R Würzner, C Lass-Flörl… - Frontiers in …, 2020 - frontiersin.org
Candida is a dominant fungal pathogen in immunocompromised hosts, leading to
opportunistic infections. Complement with its multifaceted functions is involved in the …

[HTML][HTML] Zinc Limitation Induces a Hyper-Adherent Goliath Phenotype in Candida albicans

D Malavia, LE Lehtovirta-Morley, O Alamir… - Frontiers in …, 2017 - frontiersin.org
Pathogenic microorganisms often face acute micronutrient limitation during infection due to
the action of host-mediated nutritional immunity. The human fungal pathogen Candida …

[HTML][HTML] Transcriptomic meta-analysis to identify potential antifungal targets in Candida albicans

ZA Hefny, B Ji, IE Elsemman, J Nielsen, P Van Dijck - BMC microbiology, 2024 - Springer
Background Candida albicans is a fungal pathogen causing human infections. Here we
investigated differential gene expression patterns and functional enrichment in C. albicans …