Here we present a review of the literature of influenza modeling studies, and discuss how
these models can provide insights into the future of the currently circulating novel strain of …

The emergence of resistant pathogens in response to selection pressure by drugs and their
possible disappearance when drug use is discontinued are evolutionary processes common …

Influenza A remains a significant public health challenge because of the emergence of
antigenically shifted or highly virulent strains,,,,. Antiviral resistance to available drugs such …

The emergence of highly contagious influenza A virus strains, such as the new H1N1 swine
influenza, represents a serious threat to global human health. Efforts to control emerging …

From the Publisher: Fundamental change occurs most often in one of two ways: as a" fatal
discontinuity," a sudden catastrophic event that is potentially world changing, or as a …

The influenza virus nucleoprotein (NP) is an emerging target for anti-influenza drug
development. Nucleozin (1) and its closely related derivatives had been identified as NP …

Background The response to the next influenza pandemic will likely include extensive use of
antiviral drugs (mainly oseltamivir), combined with other transmission-reducing measures …

A dramatic rise in the frequency of resistance to adamantane drugs by influenza A (H3N2)
viruses has occurred in recent years—from∼ 2% to∼ 90% in multiple countries worldwide …

Operating conditions were analyzed, thermophysical characteristics were calculated as
applied to VVER-1000 fuel rods in four-year cycle for unified core. Models for calculating gas …

Neuraminidase Inhibitors (NI) are currently the most effective drugs against influenza.
Recent cases of NI resistance are a cause for concern. To assess the danger of NI …