The vertebrate control of locomotion involves all levels of the nervous system from cortex to
the spinal cord. Here, we aim to cover all main aspects of this complex behavior, from the …

Systematic research on the physiological and anatomical characteristics of spinal cord
interneurons along with their functional output has evolved for more than one century …

Single-cell RNA sequencing data can unveil the molecular diversity of cell types. Cell type
atlases of the mouse spinal cord have been published in recent years but have not been …

The mammalian spinal cord functions as a community of cell types for sensory processing,
autonomic control, and movement. While animal models have advanced our understanding …

Although the generation of movements is a fundamental function of the nervous system, the
underlying neural principles remain unclear. As flexor and extensor muscle activities …

After spinal cord injury, tissue distal to the lesion contains undamaged cells that could
support or augment recovery. Targeting these cells requires a clearer understanding of their …

The flexibility of motor actions is ingrained in the diversity of neurons and how they are
organized into functional circuit modules, yet our knowledge of the molecular underpinning …

The flexibility of locomotor movements requires an accurate control of their start, duration,
and speed. How brainstem circuits encode and convey these locomotor parameters remains …

Locomotion is a complex behavior required for animal survival. Vertebrate locomotion
depends on spinal interneurons termed the central pattern generator (CPG), which …

Our movements and actions stem from complex processes in the central nervous system.
Precise adaptation of locomotor movements is essential for effectively interacting with the …