Enzymatic modifications of chitin, chitosan, and chitooligosaccharides

MB Kaczmarek, K Struszczyk-Swita, X Li… - … in bioengineering and …, 2019 - frontiersin.org
Chitin and its N-deacetylated derivative chitosan are two biological polymers that have
found numerous applications in recent years, but their further deployment suffers from …

Engineering status of protein for improving microbial cell factories

P Zhou, C Gao, W Song, W Wei, J Wu, L Liu… - Biotechnology …, 2024 - Elsevier
With the development of metabolic engineering and synthetic biology, microbial cell
factories (MCFs) have provided an efficient and sustainable method to synthesize a series of …

[HTML][HTML] Spatial organization of multi-enzyme biocatalytic cascades

MB Quin, KK Wallin, G Zhang… - Organic & biomolecular …, 2017 - pubs.rsc.org
Industrial biocatalysis is an economically attractive option for the production of valuable
chemicals. Our repertoire of cheap building blocks and commodity target molecules is vastly …

Metabolic engineering of Zymomonas mobilis for 2,3-butanediol production from lignocellulosic biomass sugars

S Yang, A Mohagheghi, MA Franden, YC Chou… - Biotechnology for …, 2016 - Springer
Background To develop pathways for advanced biofuel production, and to understand the
impact of host metabolism and environmental conditions on heterologous pathway …

Efficient production of 2, 3-butanediol in Saccharomyces cerevisiae by eliminating ethanol and glycerol production and redox rebalancing

S Kim, JS Hahn - Metabolic engineering, 2015 - Elsevier
Butanediol is a promising valuable chemical that can be used in various areas as a liquid
fuel and a platform chemical. Here, 2, 3-butanediol production in Saccharomyces cerevisiae …

[HTML][HTML] Protein scaffolds: a tool for multi-enzyme assembly

S Gad, S Ayakar - Biotechnology Reports, 2021 - Elsevier
The synthesis of complex molecules using multiple enzymes simultaneously in one reaction
vessel has rapidly emerged as a new frontier in the field of bioprocess technology. However …

Metabolic engineering strategies for acetoin and 2, 3-butanediol production: advances and prospects

T Yang, Z Rao, X Zhang, M Xu, Z Xu… - Critical reviews in …, 2017 - Taylor & Francis
Abstract Acetoin and 2, 3-butanediol (2, 3-BD) have a large number of industrial
applications. The production of acetoin and 2, 3-BD has traditionally relied on oil supplies …

Encapsulin nanocontainers as versatile scaffolds for the development of artificial metabolons

MC Jenkins, S Lutz - ACS Synthetic Biology, 2021 - ACS Publications
The construction of non-native biosynthetic pathways represents a powerful, modular
strategy for the production of valuable synthons and fine chemicals. Accordingly, artificially …

Theoretical and practical aspects of multienzyme organization and encapsulation

CH Abrahamson, BJ Palmero… - Annual Review of …, 2023 - annualreviews.org
The advent of biotechnology has enabled metabolic engineers to assemble heterologous
pathways in cells to produce a variety of products of industrial relevance, often in a …

Synthetic protein scaffolds for the colocalisation of co-acting enzymes

J Vanderstraeten, Y Briers - Biotechnology Advances, 2020 - Elsevier
Nature relies on complexes of colocated enzymes to efficiently perform multiple catalytic
steps. Such enzyme colocalisation promotes substrate channelling, enhances the activity of …