Capsaicin—The major bioactive ingredient of chili peppers: Bio-efficacy and delivery systems

M Lu, C Chen, Y Lan, J Xiao, R Li, J Huang, Q Huang… - Food & function, 2020 - pubs.rsc.org
Capsaicin is the primary bioactive substance in red chili peppers, which produces the
pungent flavor. During the past few decades, pharmacological benefits of capsaicin and its …

Effects and mechanisms of edible and medicinal plants on obesity: An updated review

AO Shang, RY Gan, XY Xu, QQ Mao… - Critical Reviews in …, 2021 - Taylor & Francis
In recent years, obesity has become a global public health issue. It is closely associated with
the occurrence of several chronic diseases, such as diabetes and cardiovascular diseases …

The gut microbiota metabolite capsiate regulate SLC2A1 expression by targeting HIF‐1α to inhibit knee osteoarthritis‐induced ferroptosis

Z Guan, X Jin, Z Guan, S Liu, K Tao, L Luo - Aging Cell, 2023 - Wiley Online Library
Ferroptosis is an iron‐dependent cell death that has been found to aggravate the
progression of osteoarthritis (OA) and gut microbiota‐OA axis refers to the bidirectional …

Transdermal photothermal-pharmacotherapy to remodel adipose tissue for obesity and metabolic disorders

P Zan, A Than, W Zhang, HX Cai, W Zhao, P Chen - ACS nano, 2022 - ACS Publications
Despite the increasing prevalence of obesity, the current medications, which act indirectly on
the central nervous system to suppress appetite or on the gastrointestinal tract to inhibit fat …

Extraction, purification, bioactivity and pharmacological effects of capsaicin: a review

F Wang, Y Xue, L Fu, Y Wang, M He… - Critical Reviews in …, 2022 - Taylor & Francis
Abstract Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide), a well-known vanilloid, which
is the main spicy component in chili peppers, showing several biological activities and the …

[HTML][HTML] Current evidence to propose different food supplements for weight loss: A comprehensive review

M Watanabe, R Risi, D Masi, A Caputi, A Balena… - Nutrients, 2020 - mdpi.com
The use of food supplements for weight loss purposes has rapidly gained popularity as the
prevalence of obesity increases. Navigating through the vast, often low quality, literature …

[HTML][HTML] Unravelling the therapeutic potential of nano-delivered functional foods in chronic respiratory diseases

DD Clarence, KR Paudel, B Manandhar, SK Singh… - Nutrients, 2022 - mdpi.com
Chronic inflammation of the respiratory tract is one of the most concerning public health
issues, as it can lead to chronic respiratory diseases (CRDs), some of which are more …

[HTML][HTML] Capsaicin for weight control:“Exercise in a pill”(or just another fad)?

A Szallasi - Pharmaceuticals, 2022 - mdpi.com
Medical management of obesity represents a large unmet clinical need. Animal experiments
suggest a therapeutic potential for dietary capsaicin, the pungent ingredient in hot chili …

Enhancing analgesic and anti-inflammatory effects of capsaicin when loaded into olive oil nanoemulsion: An in vivo study

Z Ghiasi, F Esmaeli, M Aghajani… - International Journal of …, 2019 - Elsevier
Topical preparations of capsaicin, the major pungent ingredient of hot pepper, are being
used for management of pain and inflammatory disorders. Purpose of this study was to use …

Capsicum annuum L. and its bioactive constituents: A critical review of a traditional culinary spice in terms of its modern pharmacological potentials with toxicological …

SK Mandal, SK Rath, R Logesh, SK Mishra… - Phytotherapy …, 2023 - Wiley Online Library
Capsicum annuum L., commonly known as chili pepper, is used as an important spice
globally and as a crude drug in many traditional medicine systems. The fruits of C. annuum …