Cell death mechanisms in stroke and novel molecular and cellular treatment options
E Sekerdag, I Solaroglu… - Current …, 2018 - ingentaconnect.com
As a result of ischemia or hemorrhage, blood supply to neurons is disrupted which
subsequently promotes a cascade of pathophysiological responses resulting in cell loss …
subsequently promotes a cascade of pathophysiological responses resulting in cell loss …
Targeting myeloperoxidase (MPO) mediated oxidative stress and inflammation for reducing brain ischemia injury: Potential application of natural compounds
Oxidative stress and inflammation are two critical pathological processes of cerebral
ischemia-reperfusion injury. Myeloperoxidase (MPO) is a critical inflammatory enzyme and …
ischemia-reperfusion injury. Myeloperoxidase (MPO) is a critical inflammatory enzyme and …
The neuroprotective effects of carvacrol on ischemia/reperfusion-induced hippocampal neuronal impairment by ferroptosis mitigation
X Guan, X Li, X Yang, J Yan, P Shi, L Ba, Y Cao… - Life sciences, 2019 - Elsevier
Objective Cerebral ischemia is the most common type of neuronal injury and is
characterized by a reduction in the function and number of hippocampal neurons. Carvacrol …
characterized by a reduction in the function and number of hippocampal neurons. Carvacrol …
[HTML][HTML] The mechanism of ferroptosis regulating oxidative stress in ischemic stroke and the regulation mechanism of natural pharmacological active components
K Yang, L Zeng, X Yuan, S Wang, A Ge, H Xu… - Biomedicine & …, 2022 - Elsevier
Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …
worldwide due to their high morbidity and mortality and limitations in clinical treatment …
Neuroprotective phytochemicals in experimental ischemic stroke: mechanisms and potential clinical applications
Ischemic stroke is a challenging disease with high mortality and disability rates, causing a
great economic and social burden worldwide. During ischemic stroke, ionic imbalance and …
great economic and social burden worldwide. During ischemic stroke, ionic imbalance and …
Targeting ferroptosis as a promising therapeutic strategy for ischemia-reperfusion injury
Y Pan, X Wang, X Liu, L Shen, Q Chen, Q Shu - Antioxidants, 2022 - mdpi.com
Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …
contributes to pathological damage in various conditions, including ischemic stroke …
Exosomes secreted by adipose-derived stem cells contribute to angiogenesis of brain microvascular endothelial cells following oxygen–glucose deprivation in vitro …
Y Yang, Y Cai, Y Zhang, J Liu, Z Xu - Journal of Molecular Neuroscience, 2018 - Springer
Adipose-derived stem cells (ADSCs) have been demonstrated to promote cerebral vascular
remodeling processes after stroke. However, the exact molecular mechanism by which …
remodeling processes after stroke. However, the exact molecular mechanism by which …
Neuronal survival in the brain: neuron type-specific mechanisms
U Pfisterer, K Khodosevich - Cell death & disease, 2017 - nature.com
Neurogenic regions of mammalian brain produce many more neurons that will eventually
survive and reach a mature stage. Developmental cell death affects both embryonically …
survive and reach a mature stage. Developmental cell death affects both embryonically …
A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol
M Nazıroğlu - Metabolic brain disease, 2022 - Springer
The overload cytosolic free Ca2+ (cCa2+) influx-mediated excessive generation of oxidative
stress in the pathophysiological conditions induces neuronal and cellular injury via the …
stress in the pathophysiological conditions induces neuronal and cellular injury via the …
An antagomir to microRNA-106b-5p ameliorates cerebral ischemia and reperfusion injury in rats via inhibiting apoptosis and oxidative stress
P Li, M Shen, F Gao, J Wu, J Zhang, F Teng… - Molecular …, 2017 - Springer
We previously observed that microRNA miR-106b-5p significantly increased in serum of
patients with acute ischemic stroke. The present study was to determine whether miR-106b …
patients with acute ischemic stroke. The present study was to determine whether miR-106b …