[HTML][HTML] Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

[HTML][HTML] Anti-quorum sensing activity of probiotics: the mechanism and role in food and gut health

MK Salman, J Abuqwider, G Mauriello - Microorganisms, 2023 - mdpi.com
Background: Quorum sensing (QS) is a cell-to-cell communication mechanism that occurs
between inter-and intra-bacterial species and is regulated by signaling molecules called …

Enzyme-responsive microneedle patch for bacterial infection and accelerated healing of diabetic wounds

S Wu, B Qin, X Tang, T Cui, S Yin, H Dong, Y Liu… - Chemical Engineering …, 2023 - Elsevier
Chronic diabetic wounds are caused by an array of pathologies. Pathogenic bacteria such
as S. aureus can easily invade hosts with deficient immunity. In this study, we developed a …

[HTML][HTML] The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia

C Langouët-Astrié, K Oshima, SA McMurtry, Y Yang… - Cell reports, 2022 - cell.com
Influenza infection is substantially worsened by the onset of secondary pneumonia caused
by bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). The bidirectional …

Celastrol Combats Methicillin‐Resistant Staphylococcus aureus by Targeting Δ1‐Pyrroline‐5‐Carboxylate Dehydrogenase

Z Yuan, J Wang, Q Qu, Z Zhu, M Xu, M Zhao… - Advanced …, 2023 - Wiley Online Library
The emergence and rapid spread of methicillin‐resistant Staphylococcus aureus (MRSA)
raise a critical need for alternative therapeutic options. New antibacterial drugs and targets …

[HTML][HTML] Staphylococcus aureus biofilm: Formulation, regulatory, and emerging natural products-derived therapeutics

X Wu, H Wang, J Xiong, GX Yang, JF Hu, Q Zhu… - Biofilm, 2024 - Elsevier
Staphylococcus aureus can readily form biofilm which enhances the drug-resistance,
resulting in life-threatening infections involving different organs. Biofilm formation occurs due …

Staphylococcus aureus enters viable-but-nonculturable state in response to chitooligosaccharide stress by altering metabolic pattern and transmembrane transport …

J Li, C Liu, S Wang, X Mao - Carbohydrate Polymers, 2024 - Elsevier
Although chitooligosaccharide (COS) has attracted the attention of some researchers due to
its good solubility and broad-spectrum antibacterial activity, our study found that …

Understanding mechanisms of virulence in MRSA: implications for antivirulence treatment strategies

RC Hsieh, R Liu, DJ Burgin, M Otto - Expert Review of Anti-infective …, 2023 - Taylor & Francis
ABSTRACT Introduction Methicillin-resistant Staphylococcus aureus (MRSA) is a
widespread pathogen, often causing recurrent and deadly infections in the hospital and …

Regulation of bacterial two-component systems by cardiolipin

WS Yeo, S Dyzenhaus, VJ Torres… - Infection and …, 2023 - Am Soc Microbiol
The regulation of membrane protein activity for cellular functions is critically dependent on
the composition of phospholipid membranes. Cardiolipin, a unique phospholipid found in …

Inside the phagosome: a bacterial perspective

MB Hampton, N Dickerhof - Immunological Reviews, 2023 - Wiley Online Library
The neutrophil phagosome is one of the most hostile environments that bacteria must face
and overcome if they are to succeed as pathogens. Targeting bacterial defense mechanisms …