Forks in the road for CAR T and CAR NK cell cancer therapies
OK Dagher, AD Posey Jr - Nature Immunology, 2023 - nature.com
The advent of chimeric antigen receptor (CAR) T cell therapy has resulted in unprecedented
long-term clearance of relapse/refractory hematological malignancies in both pediatric and …
long-term clearance of relapse/refractory hematological malignancies in both pediatric and …
Development of NK cell-based cancer immunotherapies through receptor engineering
A Page, N Chuvin, J Valladeau-Guilemond… - Cellular & Molecular …, 2024 - nature.com
Natural killer (NK) cell-based immunotherapies are attracting increasing interest in the field
of cancer treatment. Early clinical trials have shown promising outcomes, alongside …
of cancer treatment. Early clinical trials have shown promising outcomes, alongside …
Breakthrough of solid tumor treatment: CAR-NK immunotherapy
W Wang, Y Liu, Z He, L Li, S Liu, M Jiang, B Zhao… - Cell Death …, 2024 - nature.com
As the latest and most anticipated method of tumor immunotherapy, CAR-NK therapy has
received increasing attention in recent years, and its safety and high efficiency have …
received increasing attention in recent years, and its safety and high efficiency have …
Chimeric antigen receptor engineered natural killer cells for cancer therapy
Y Zhang, W Zhou, J Yang, J Yang, W Wang - Experimental Hematology & …, 2023 - Springer
Natural killer (NK) cells, a unique component of the innate immune system, are inherent
killers of stressed and transformed cells. Based on their potent capacity to kill cancer cells …
killers of stressed and transformed cells. Based on their potent capacity to kill cancer cells …
Emerging roles of CAR-NK cell therapies in tumor immunotherapy: current status and future directions
Y Zhong, J Liu - Cell Death Discovery, 2024 - nature.com
Cancer immunotherapy harnesses the body's immune system to combat malignancies,
building upon an understanding of tumor immunosurveillance and immune evasion …
building upon an understanding of tumor immunosurveillance and immune evasion …
Cytokine modification of adoptive chimeric antigen receptor immunotherapy for glioblastoma
KD Pawlowski, JT Duffy, S Gottschalk, IV Balyasnikova - Cancers, 2023 - mdpi.com
Simple Summary Chimeric antigen receptor (CAR) cell-based therapy is a promising
treatment approach for glioblastoma, a fatal brain cancer with limited treatment options …
treatment approach for glioblastoma, a fatal brain cancer with limited treatment options …
CAR-NK cell therapy for glioblastoma: what to do next?
Q Xiong, J Zhu, Y Zhang, H Deng - Frontiers in oncology, 2023 - frontiersin.org
Glioblastoma is a malignant tumor with the highest morbidity and mortality in the central
nervous system. Conventional surgical resection combined with radiotherapy or …
nervous system. Conventional surgical resection combined with radiotherapy or …
CAR NK cell therapy for the treatment of metastatic melanoma: Potential & prospects
Melanoma is among the most lethal forms of cancer, accounting for 80% of deaths despite
comprising just 5% of skin cancer cases. Treatment options remain limited due to the genetic …
comprising just 5% of skin cancer cases. Treatment options remain limited due to the genetic …
Insight into the Progress in CAR-T Cell Therapy and Combination with Other Therapies for Glioblastoma
T Liang, Y Song, L Gu, Y Wang… - International Journal of …, 2023 - Taylor & Francis
Glioblastoma (GBM) is the most common malignant primary brain cancer in adults. It is
always resistant to existing treatments, including surgical resection, postoperative …
always resistant to existing treatments, including surgical resection, postoperative …
Chimeric antigen receptor natural killer cells: a promising antitumor immunotherapy
Y Wang, S Jin, Q Zhuang, N Liu, R Chen, SA Adam… - MedComm, 2023 - Wiley Online Library
Chimeric antigen receptor (CAR) T cells have been successfully used in adoptive cell
therapy for malignancies. However, some obstacles, including side effects such as graft …
therapy for malignancies. However, some obstacles, including side effects such as graft …