Mechanisms of alloimmunization in sickle cell disease

KE Hudson, RM Fasano, MS Karafin… - Current opinion in …, 2019 - journals.lww.com
The inflammation and immune dysregulation associated with SCD may be therapeutic
targets for preventing the formation of antibodies and/or for mitigating the dangers of existing …

Blood donors with thalassemic trait, glucose-6-phosphate dehydrogenase deficiency trait, and sickle cell trait and their blood products: current status and future …

E Noulsri, S Lerdwana - Laboratory Medicine, 2023 - academic.oup.com
The use of blood products for different medical purposes has increased in recent years. To
meet increasing demand, some blood centers allow volunteer donors with thalassemic trait …

Utilization of 18s ribosomal RNA LAMP for detecting Plasmodium falciparum in microscopy and rapid diagnostic test negative patients

E Aninagyei, AA Boakye, CO Tettey, KA Ntiri, SO Ofori… - Plos one, 2022 - journals.plos.org
In this study, Plasmodium falciparum was detected in patients that were declared negative
for malaria microscopy and rapid diagnostic test kit (mRDT), using Plasmodium 18s rRNA …

Comparative evaluation of the diagnostic accuracies of four different malaria rapid diagnostic test kits available in Ghana

E Aninagyei, JG Deku, KT Yemofio, E Quainoo, KA Ntiri… - Plos one, 2024 - journals.plos.org
Malaria rapid diagnostic test (mRDT) kit is one of the techniques for diagnosing malaria. Due
to its inherent advantages over the microscopy technique, several brands of the kit have …

Evaluating 18s-rRNA LAMP and selective whole genome amplification (sWGA) assay in detecting asymptomatic Plasmodium falciparum infections in blood donors

E Aninagyei, S Smith-Graham, A Boye, A Egyir-Yawson… - Malaria journal, 2019 - Springer
Background Undesirable consequences of donor Plasmodium falciparum parasitaemia on
stored donor blood have been reported. Therefore, it is imperative that all prospective blood …

Elevated IL‐12, TNF‐α, and TNF‐α/IL‐10 Ratios in Stored Plasmodium falciparum‐Infected Whole Blood: Implications for Safe Haemotransfusion

E Aninagyei, P Adu, A Egyir-Yawson… - Journal of …, 2020 - Wiley Online Library
Although Plasmodium falciparum infections in blood donors have been reported, the impact
of parasitaemia on cytokine levels in stored whole blood has not been explored. This study …

Reconsidering sickle cell trait testing of red blood cell units allocated to children with sickle cell disease

OI Hajjaj, C Cserti‐Gazdewich, L Dumevska… - …, 2023 - Wiley Online Library
Background Sickle cell trait (SCT) testing of red blood cell (RBC) units is sometimes
performed to identify and divert units containing hemoglobin S (HbS). Recipients …

Elevation of free triiodothyronine (fT3) levels by Plasmodium falciparum independent of thyroid stimulating hormone (TSH) in children with uncomplicated malaria

H Kwansa‐Bentum, E Aninagyei… - Journal of Clinical …, 2024 - Wiley Online Library
Background Malaria parasites have a devastating effect on the infected host. However, there
is a paucity of data on the effect of Plasmodium falciparum on thyroid hormones. Methods …

Effect of Asymptomatic Plasmodium falciparum Parasitaemia on Platelets Thrombogenicity in Blood Donors

E Aninagyei, P Adu, T Rufai, P Ampomah… - Indian Journal of …, 2021 - Springer
Currently, blood donors in Ghana are not screened for malaria parasites. Therefore, this
study assessed platelet thrombogenicity in blood donors infected asymptomatically with …

Donors with repeated blood product discards for filtration problems, clots or hemolysis: Causes and follow‐up

N Díaz Padilla, JC Wiersum‐Osselton… - …, 2024 - Wiley Online Library
Introduction Sanquin donor medicine department is informed when donations or their
components are rejected. This can occur isolated or frequently. It is undesirable because the …