[HTML][HTML] Gastrinoma

RT Jensen, T Ito - Endotext [Internet], 2023 - ncbi.nlm.nih.gov
Gastrinomas are neuroendocrine neoplasms (NENs), that occur primarily in the duodenum
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …

Acid suppression therapy: where do we go from here?

C Scarpignato, I Pelosini, F Di Mario - Digestive Diseases, 2006 - karger.com
The dramatic success of pharmacological acid suppression in healing peptic ulcers and
managing patients with gastroesophageal reflux disease (GERD) has been reflected in the …

Effect of proton-pump inhibitor therapy on serum chromogranin a level

I Pregun, L Herszényi, M Juhász, P Miheller, I Hritz… - Digestion, 2011 - karger.com
Background: The neuroendocrine marker, chromogranin A (CgA) increases during medium-
or long-term proton-pump inhibitor (PPI) treatment. Aims: To analyze the effect of ultra-short …

Proton pump inhibitors (PPIs) may cause gastric cancer–clinical consequences

HL Waldum, Ø Sørdal, R Fossmark - Scandinavian journal of …, 2018 - Taylor & Francis
Recently, two epidemiological studies showed that long-term treatment with proton pump
inhibitors (PPIs) increased the risk of gastric cancer. It is well known that hypergastrinemia …

Hypergastrinemia

S Dacha, M Razvi, J Massaad, Q Cai… - Gastroenterology …, 2015 - academic.oup.com
Gastrin is an important hormone of the digestive system, which assists gastric acid secretion.
It may be pathologically elevated in conditions such as Zollinger-Ellison syndrome, or due to …

Insights into effects/risks of chronic hypergastrinemia and lifelong ppi treatment in man based on studies of patients with Zollinger–Ellison syndrome

L Lee, I Ramos-Alvarez, T Ito, RT Jensen - International Journal of …, 2019 - mdpi.com
The use of proton pump inhibitors (PPIs) over the last 30 years has rapidly increased both in
the United States and worldwide. PPIs are not only very widely used both for approved …

Evaluation of the effects of medium‐term (57‐day) omeprazole administration and of omeprazole discontinuation on serum gastrin and serum chromogranin A …

B Clark, C Steel, J Vokes, JR Shan… - Journal of veterinary …, 2023 - Wiley Online Library
Background Rebound gastric hyperacidity (RGH) secondary to hypergastrinemia has been
suggested to contribute to the rapid recurrence of equine squamous gastric disease (ESGD) …

Zollinger-Ellison syndrome revisited: diagnosis, biologic markers, associated inherited disorders, and acid hypersecretion

F Gibril, RT Jensen - Current Gastroenterology Reports, 2004 - Springer
Despite general awareness of Zollinger-Ellison syndrome (ZES) by most physicians and
more than 3000 articles written about it since 1955, the diagnosis of ZES is still delayed for a …

A comprehensive evaluation of fasting serum gastrin-17 as a predictor of diseased stomach in Chinese population

L Sun, H Tu, J Liu, Y Gong, Q Xu, J Jing… - Scandinavian Journal …, 2014 - Taylor & Francis
Background and aim. Fasting serum gastrin-17 (FsG17) is considered as a noninvasive
biomarker reflecting the structure and functional status of gastric mucosa, but its clinical …

[HTML][HTML] Long-Term Proton Pump Inhibitor–Acid Suppressive Treatment Can Cause Vitamin B12 Deficiency in Zollinger–Ellison Syndrome (ZES) Patients

T Ito, I Ramos-Alvarez, RT Jensen - International Journal of Molecular …, 2024 - mdpi.com
Whether the long-term treatment of patients with proton pump inhibitors (PPIs) with different
diseases [GERD, Zollinger–Ellison syndrome (ZES), etc.] can result in vitamin B12 (VB12) …