Evolutionary Emergence of Drug Resistance in Candida Opportunistic Pathogens
E Ksiezopolska, T Gabaldón - Genes, 2018 - mdpi.com
Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …
medical concern. In developed countries, the incidence of Candida infections is increasing …
The quiet and underappreciated rise of drug-resistant invasive fungal pathogens
A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
Candida glabrata: a review of its features and resistance
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and
vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous …
vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous …
Candida glabrata: A Lot More Than Meets the Eye
Candida glabrata is an opportunistic human fungal pathogen that causes superficial
mucosal and life-threatening bloodstream infections in individuals with a compromised …
mucosal and life-threatening bloodstream infections in individuals with a compromised …
Candida glabrata Biofilms: How Far Have We Come?
Infections caused by Candida species have been increasing in the last decades and can
result in local or systemic infections, with high morbidity and mortality. After Candida …
result in local or systemic infections, with high morbidity and mortality. After Candida …
Aneuploidy in yeast: Segregation error or adaptation mechanism?
C Gilchrist, R Stelkens - Yeast, 2019 - Wiley Online Library
Aneuploidy is the loss or gain of chromosomes within a genome. It is often detrimental and
has been associated with cell death and genetic disorders. However, aneuploidy can also …
has been associated with cell death and genetic disorders. However, aneuploidy can also …
Evolutionary genomics of yeast pathogens in the Saccharomycotina
T Gabaldón, MA Naranjo-Ortíz… - FEMS yeast …, 2016 - academic.oup.com
Saccharomycotina comprises a diverse group of yeasts that includes numerous species of
industrial or clinical relevance. Opportunistic pathogens within this clade are often assigned …
industrial or clinical relevance. Opportunistic pathogens within this clade are often assigned …
Adhesins in Candida glabrata
B Timmermans, A De Las Peñas, I Castaño… - Journal of Fungi, 2018 - mdpi.com
The human fungal pathogen Candida glabrata is causing more and more problems in
hospitals, as this species shows an intrinsic antifungal drug resistance or rapidly becomes …
hospitals, as this species shows an intrinsic antifungal drug resistance or rapidly becomes …
Patterns of genomic variation in the opportunistic pathogen Candida glabrata suggest the existence of mating and a secondary association with humans
Candida glabrata is an opportunistic fungal pathogen that ranks as the second most
common cause of systemic candidiasis. Despite its genus name, this yeast is more closely …
common cause of systemic candidiasis. Despite its genus name, this yeast is more closely …
Genetic Drivers of Multidrug Resistance in Candida glabrata
KR Healey, C Jimenez Ortigosa, E Shor… - Frontiers in …, 2016 - frontiersin.org
Both the incidence of invasive fungal infections and rates of multidrug resistance associated
with fungal pathogen Candida glabrata have increased in recent years. In this perspective …
with fungal pathogen Candida glabrata have increased in recent years. In this perspective …