Skeletal muscle injuries occur frequently in daily life and exercise. Understanding the
mechanisms of regeneration is critical for accelerating the repair and regeneration of …

Histone deacetylases (HDACs) are enzymes that regulate the deacetylation of numerous
histone and non-histone proteins, thereby affecting a wide range of cellular processes …

Stem cells secrete paracrine factors including extracellular vesicles (EVs) which can
mediate cellular communication and support the regeneration of injured tissues. Reduced …

Skeletal muscle, which comprises a significant portion of the body, is responsible for vital
functions such as movement, metabolism, and overall health. However, severe injuries often …

Engineering biomimetic tissue implants with human induced pluripotent stem cells (hiPSCs)
holds promise for repairing volumetric tissue loss. However, these implants face challenges …

Sarcopenia is an age-associated loss of skeletal muscle mass, strength, and function,
accompanied by severe adverse health outcomes, such as falls and fractures, functional …

Duchenne muscular dystrophy (DMD) is caused by loss-of-function mutations in the
dystrophin gene on chromosome Xp21. Disruption of the dystrophin–glycoprotein complex …

The failure of muscle to repair after injury during aging may be a major contributor to muscle
mass loss. We recently generated muscle progenitor cells (MPCs) from human-induced …

Duchenne muscular dystrophy (DMD) is a hereditary disease characterized by severe
muscle weakness resulting from DYSTROPHIN deficiency-associated damage. Muscle …

Human induced pluripotent stem cells (hiPSCs) possess immense potential as a valuable
source for the generation of a wide variety of human cells, yet monitoring the early cell …