Over the past 2000 years, tuberculosis (TB) has claimed more lives than any other infectious
disease. In 2020 alone, TB was responsible for 1.5 million deaths worldwide, comparable to …

The necessity for the discovery of innovative antimicrobials to treat life-threatening diseases
has increased as multidrug-resistant bacteria has spread. Due to antibiotics' availability over …

Indole-containing small molecules have been reported to have diverse pharmacological
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …

The emergence of drug-resistant mycobacteria, including Mycobacterium tuberculosis (Mtb)
and non-tuberculous mycobacteria (NTM), poses an increasing global threat that urgently …

Aeromonas salmonicida is a well-known cold-water pathogenic bacterium. Previously, we
reported the first isolation of pathogenic A. salmonicida from diseased Epinephelus …

Introduction Tuberculosis remains a significant concern in global public health due to its
intricate biology and propensity for developing antibiotic resistance. Discovering new drugs …

Microbial amino acid biosynthetic pathways are underexploited for the development of anti-
bacterial agents. N-acetyl glutamate synthase (ArgA) catalyses the first committed step in L …

Mycobacterium tuberculosis (M. tuberculosis) encodes an essential enzyme acetyl ornithine
aminotransferase ArgD (Rv1655) of arginine biosynthetic pathway which plays crucial role …

The enzyme encoded by slr1022 gene from Synechocystis sp. PCC6803 was reported to
function as N-acetylornithine aminotransferase, γ-aminobutyric acid aminotransferase, and …

The pandemic COVID-19, caused by SARS-COV-2, has been a global concern and burden
since April 2020 due to high contagiousness and pathogenesis. A great effort is being …