As the world pledges to significantly cut carbon emissions, the demand for sustainable and
clean energy has now become more important than ever. This includes both production and …

Fossil based resources are a major contributor to energy and chemicals to modern-day
development. The negative environmental impacts of fossil-based resources accompanied …

Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …

Abstract NAD (P) H-dependent oxidoreductases catalyze the reduction or oxidation of a
substrate coupled to the oxidation or reduction, respectively, of a nicotinamide adenine …

Advanced biofuels produced by microorganisms have similar properties to petroleum-based
fuels, and can'drop in'to the existing transportation infrastructure. However, producing these …

Environmental deterioration, global climate change, and consequent increases in pollution-
related health problems among populations have been attributed to growing consumption of …

The design and optimization of biosynthetic pathways for industrially relevant, non-model
organisms is challenging due to transformation idiosyncrasies, reduced numbers of …

Butanediol (BDO) is an important commodity chemical used to manufacture over 2.5 million
tons annually of valuable polymers, and it is currently produced exclusively through …

Growing concerns over limited fossil resources and associated environmental problems are
motivating the development of sustainable processes for the production of chemicals, fuels …

One-step multiple gene disruption in the model organism Saccharomyces cerevisiae is a
highly useful tool for both basic and applied research, but it remains a challenge. Here, we …