The mechanistic target of rapamycin (mTOR) signaling pathway is a crucial cellular
signaling hub that, like the nervous system itself, integrates internal and external cues to …

Background Obesity develops due to an imbalance in energy homeostasis, wherein energy
intake exceeds energy expenditure. Accumulating evidence shows that manipulations of …

Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …

The AMP‐activated serine/threonine protein kinase (AMPK) is a sensor of cellular energy
status found in all eukaryotes that is activated under conditions of low intracellular ATP …

Adenylate kinase and downstream AMP signaling is an integrated metabolic monitoring
system which reads the cellular energy state in order to tune and report signals to metabolic …

Context Energy balance is critical for survival and health, and control of food intake is an
integral part of this process. This report reviews hormonal signals that influence food intake …

The mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of metabolic
and nutrient cues that integrates environmental inputs into downstream signaling pathways …

There is a discrepancy between the in vitro anergic state of CD4+ CD25 hi FoxP3+
regulatory T (Treg) cells and their in vivo proliferative capability. The underlying mechanism …

Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth
hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n …

Valine, leucine and isoleucine form the small group of branched-chain amino acids (BCAAs)
classified by their small branched hydrocarbon residues. Unlike animals, plants are able to …