The stiffness of living tissues and its implications for tissue engineering
The past 20 years have witnessed ever-growing evidence that the mechanical properties of
biological tissues, from nanoscale to macroscale dimensions, are fundamental for cellular …
biological tissues, from nanoscale to macroscale dimensions, are fundamental for cellular …
[HTML][HTML] Natural polymeric scaffolds in bone regeneration
M Filippi, G Born, M Chaaban… - … in bioengineering and …, 2020 - frontiersin.org
Despite considerable advances in microsurgical techniques over the past decades, bone
tissue remains a challenging arena to obtain a satisfying functional and structural restoration …
tissue remains a challenging arena to obtain a satisfying functional and structural restoration …
[HTML][HTML] The role of network architecture in collagen mechanics
Collagen forms fibrous networks that reinforce tissues and provide an extracellular matrix for
cells. These networks exhibit remarkable strain-stiffening properties that tailor the …
cells. These networks exhibit remarkable strain-stiffening properties that tailor the …
Bioactive 2D nanomaterials for neural repair and regeneration
X He, Y Zhu, B Ma, X Xu, R Huang, L Cheng… - Advanced Drug Delivery …, 2022 - Elsevier
Biomaterials have provided promising strategies towards improving the functions of injured
tissues of the nervous system. Recently, 2D nanomaterials, such as graphene, layered …
tissues of the nervous system. Recently, 2D nanomaterials, such as graphene, layered …
[HTML][HTML] Passive myocardial mechanical properties: meaning, measurement, models
R Emig, CM Zgierski-Johnston, V Timmermann… - Biophysical …, 2021 - Springer
Passive mechanical tissue properties are major determinants of myocardial contraction and
relaxation and, thus, shape cardiac function. Tightly regulated, dynamically adapting …
relaxation and, thus, shape cardiac function. Tightly regulated, dynamically adapting …
[HTML][HTML] Deciphering structural biological materials: Viewing from the mechanics perspective and their prospects
Structural biological materials are multiphase composite materials in nature. Their
mechanical properties are extraordinary despite their weak constituents. This review aims to …
mechanical properties are extraordinary despite their weak constituents. This review aims to …
Mechanical roles in formation of oriented collagen fibers
J Lin, Y Shi, Y Men, X Wang, J Ye… - Tissue Engineering Part …, 2020 - liebertpub.com
Collagen is a structural protein that is widely present in vertebrates, being usually distributed
in tissues in the form of fibers. In living organisms, fibers are organized in different …
in tissues in the form of fibers. In living organisms, fibers are organized in different …
[HTML][HTML] Dynamic filopodial forces induce accumulation, damage, and plastic remodeling of 3D extracellular matrices
The mechanical properties of the extracellular matrix (ECM)–a complex, 3D, fibrillar scaffold
of cells in physiological environments–modulate cell behavior and can drive tissue …
of cells in physiological environments–modulate cell behavior and can drive tissue …
[HTML][HTML] Nanomechanics of type I collagen
Type I collagen is the predominant collagen in mature tendons and ligaments, where it gives
them their load-bearing mechanical properties. Fibrils of type I collagen are formed by the …
them their load-bearing mechanical properties. Fibrils of type I collagen are formed by the …
[HTML][HTML] Multiscale mechanical analysis of the elastic modulus of skin
A Wahlsten, A Stracuzzi, I Lüchtefeld, G Restivo… - Acta Biomaterialia, 2023 - Elsevier
The mechanical properties of the skin determine tissue function and regulate dermal cell
behavior. Yet measuring these properties remains challenging, as evidenced by the large …
behavior. Yet measuring these properties remains challenging, as evidenced by the large …