SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

Since the beginning of the COVID-19 pandemic, reduced incidence of many viral and
bacterial infections has been reported in children: bronchiolitis, varicella, measles, pertussis …

Background Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract
infection and hospitalization in infants. Nirsevimab is a monoclonal antibody to the RSV …

The burning of fossil fuels–especially coal, petrol, and diesel–is a major source of airborne
fine particulate matter (PM 2.5), and a key contributor to the global burden of mortality and …

Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases.
However, in vulnerable populations, such as newborns, infants, the elderly and immune …

Viral bronchiolitis is the most common cause of admission to hospital for infants in high-
income countries. Respiratory syncytial virus accounts for 60–80% of bronchiolitis …

Many nations are pursuing the rollout of SARS-CoV-2 vaccines as an exit strategy from
unprecedented COVID-19-related restrictions. However, the success of this strategy relies …

Bacteria that colonize the human gastrointestinal tract are essential for good health. The gut
microbiota has a critical role in pulmonary immunity and host's defense against viral …

Organoids are in vitro–cultured three-dimensional structures that recapitulate key aspects of
in vivo organs. They can be established from pluripotent stem cells and from adult stem …

Background We have previously estimated that respiratory syncytial virus (RSV) was
associated with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) …