Red blood cell alloimmunization in sickle cell disease: pathophysiology, risk factors, and transfusion management

K Yazdanbakhsh, RE Ware… - Blood, The Journal of …, 2012 - ashpublications.org
Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell
disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious …

Red blood cell transfusion in clinical practice

HG Klein, DR Spahn, JL Carson - The Lancet, 2007 - thelancet.com
Every year, about 75 million units of blood are collected worldwide. Red blood cell (RBC)
transfusion is one of the few treatments that adequately restore tissue oxygenation when …

[PDF][PDF] Guidelines for pre‐transfusion compatibility procedures in blood transfusion laboratories

British Committee for Standards in … - Transfusion …, 2013 - thebloodproject.com
Section 3 SAMPLES AND DOCUMENTATION Section 4 ABO AND D GROUPING Section 5
ANTIBODY SCREENING Section 6 ANTIBODY IDENTIFICATION Section 7 SELECTION …

[HTML][HTML] Transfusiones en pacientes con pruebas de compatibilidad positivas y en aquellos con anemia hemolítica autoinmune

JM Aristizábal Aristizábal, JD Torres - Iatreia, 2007 - scielo.org.co
Es frecuente la presencia de pruebas de compatibilidad positivas en pacientes que
requieren soporte transfusional. Los pacientes con anemia hemolítica autoinmune …

Challenges of alloimmunization in patients with haemoglobinopathies

ST Chou, RI Liem, AA Thompson - British journal of …, 2012 - Wiley Online Library
Red blood cell (RBC) transfusions can be life‐sustaining in chronic inherited anaemias,
such as thalassaemia, and the indications for blood transfusions in patients with sickle cell …

Risk factors for red blood cell alloimmunization in the Recipient Epidemiology and Donor Evaluation Study (REDS‐III) database

MS Karafin, M Westlake, RG Hauser… - British journal of …, 2018 - Wiley Online Library
Despite the significance of red blood cell (RBC) alloimmunization, the lack of standardized
registries in the US has prevented the completion of large studies. Data from 3· 5 years of …

Red blood cell alloimmunization in the pregnant patient

J Webb, M Delaney - Transfusion medicine reviews, 2018 - Elsevier
Alloimmunization to red blood cell (RBC) antigens represents a challenge for physicians
caring for women of child bearing potential. Exposure to non-self RBC antigens may occur …

Blood still kills: six strategies to further reduce allogeneic blood transfusion-related mortality

EC Vamvakas, MA Blajchman - Transfusion medicine reviews, 2010 - Elsevier
After reviewing the relative frequency of the causes of allogeneic blood transfusion-related
mortality in the United States today, we present 6 possible strategies for further reducing …

Stochastic modeling of human RBC alloimmunization: evidence for a distinct population of immunologic responders

JM Higgins, SR Sloan - Blood, The Journal of the American …, 2008 - ashpublications.org
Red blood cell (RBC) transfusion is unique as a common large-scale intravenous
introduction of foreign tissue and provides a valuable opportunity to study human …

Red-blood-cell alloimmunisation in relation to antigens' exposure and their immunogenicity: a cohort study

D Evers, RA Middelburg, M de Haas… - The Lancet …, 2016 - thelancet.com
Background Matching donor red blood cells based on recipient antigens prevents
alloimmunisation. Knowledge about the immunogenicity of red-blood-cell antigens can help …