Context is everything: aneuploidy in cancer

U Ben-David, A Amon - Nature Reviews Genetics, 2020 - nature.com
Cancer is driven by multiple types of genetic alterations, which range in size from point
mutations to whole-chromosome gains and losses, known as aneuploidy. Chromosome …

An evolutionary perspective on field cancerization

K Curtius, NA Wright, TA Graham - Nature Reviews Cancer, 2018 - nature.com
Tumorigenesis begins long before the growth of a clinically detectable lesion and, indeed,
even before any of the usual morphological correlates of pre-malignancy are recognizable …

Esophageal carcinoma

AK Rustgi, HB El-Serag - New England Journal of Medicine, 2014 - Mass Medical Soc
The 5-year survival rate in esophageal cancer, although poor, has improved over the past
decade. This review discusses the epidemiologic aspects, pathogenesis, prevention, and …

ASGE guideline on screening and surveillance of Barrett's esophagus

B Qumseya, S Sultan, P Bain, L Jamil… - Gastrointestinal …, 2019 - giejournal.org
This document is the official American Society for Gastrointestinal Endoscopy guideline on
screening and surveillance in patients with Barrett's esophagus (BE) and is based on …

British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus

RC Fitzgerald, M Di Pietro, K Ragunath, Y Ang… - Gut, 2014 - gut.bmj.com
These guidelines provide a practical and evidence-based resource for the management of
patients with Barrett's oesophagus and related early neoplasia. The Appraisal of Guidelines …

Barrett's esophagus

SJ Spechler, RF Souza - New England Journal of Medicine, 2014 - Mass Medical Soc
Barrett's Esophagus | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Barrett's oesophagus patients with low-grade dysplasia can be accurately risk-stratified after histological review by an expert pathology panel

LC Duits, KN Phoa, WL Curvers, FJW Ten Kate… - Gut, 2015 - gut.bmj.com
Objective Reported malignant progression rates for low-grade dysplasia (LGD) in Barrett's
oesophagus (BO) vary widely. Expert histological review of LGD is advised, but limited data …

Epidemiology of Barrett's esophagus and esophageal adenocarcinoma

TM Runge, JA Abrams… - Gastroenterology Clinics, 2015 - gastro.theclinics.com
Barrett's esophagus (BE) is a condition in which the typical squamous epithelium of the
esophageal mucosa is replaced with columnar intestinal epithelium. 1, 2 BE is a known …

Recent developments in esophageal adenocarcinoma

J Lagergren, P Lagergren - CA: a cancer journal for clinicians, 2013 - Wiley Online Library
Answer questions and earn CME/CNE Esophageal adenocarcinoma (EAC) is characterized
by 6 striking features: increasing incidence, male predominance, lack of preventive …

Diagnosis and management of low-grade dysplasia in Barrett's esophagus: expert review from the Clinical Practice Updates Committee of the American …

S Wani, JH Rubenstein, M Vieth, J Bergman - Gastroenterology, 2016 - Elsevier
The purpose of this clinical practice update expert review is to define the key principles in
the diagnosis and management of low-grade dysplasia (LGD) in Barrett's esophagus …