Role of microRNAs, circRNAs and long noncoding RNAs in acute myeloid leukemia

Y Liu, Z Cheng, Y Pang, L Cui, T Qian, L Quan… - Journal of hematology & …, 2019 - Springer
Acute myeloid leukemia (AML) is a malignant tumor of the immature myeloid hematopoietic
cells in the bone marrow (BM). It is a highly heterogeneous disease, with rising morbidity …

Regulation of the MIR155 host gene in physiological and pathological processes

TS Elton, H Selemon, SM Elton, NL Parinandi - Gene, 2013 - Elsevier
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

Cancer Genome Atlas Research … - New England Journal of …, 2013 - Mass Medical Soc
Background Many mutations that contribute to the pathogenesis of acute myeloid leukemia
(AML) are undefined. The relationships between patterns of mutations and epigenetic …

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome

V Neudecker, M Haneklaus, O Jensen… - Journal of Experimental …, 2017 - rupress.org
MicroRNA (miRNA)-mediated RNA interference regulates many immune processes, but how
miRNA circuits orchestrate aberrant intestinal inflammation during inflammatory bowel …

miR‐223: infection, inflammation and cancer

M Haneklaus, M Gerlic, LAJ O'Neill… - Journal of internal …, 2013 - Wiley Online Library
Expression of the micro RNA miR‐223 is deregulated during influenza or hepatitis B
infection and in inflammatory bowel disease, type 2 diabetes, leukaemia and lymphoma …

Haemolysis during sample preparation alters microRNA content of plasma

MB Kirschner, SC Kao, JJ Edelman, NJ Armstrong… - PloS one, 2011 - journals.plos.org
The presence of cell-free microRNAs (miRNAs) has been detected in a range of body fluids.
The miRNA content of plasma/serum in particular has been proposed as a potential source …

The impact of hemolysis on cell-free microRNA biomarkers

MB Kirschner, JJB Edelman, SCH Kao… - Frontiers in …, 2013 - frontiersin.org
Cell-free microRNAs in plasma and serum have become a promising source of biomarkers
for various diseases. Despite rapid progress in this field, there remains a lack of consensus …

Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in Eμ-miR155 transgenic mice

S Costinean, N Zanesi, Y Pekarsky… - Proceedings of the …, 2006 - National Acad Sciences
MicroRNAs (miRNAs) represent a newly discovered class of posttranscriptional regulatory
noncoding small RNAs that bind to targeted mRNAs and either block their translation or …

A potential role of microvesicle-containing miR-223/142 in lung inflammation

D Zhang, H Lee, X Wang, M Groot, L Sharma… - Thorax, 2019 - thorax.bmj.com
Background Uncontrolled lung inflammation is one of the prominent features in the
pathogenesis of lung infection-associated acute lung injury (ALI). Microvesicles (MVs) are …

MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death

R Schickel, B Boyerinas, SM Park, ME Peter - Oncogene, 2008 - nature.com
Micro (mi) RNAs are small, highly conserved noncoding RNAs that control gene expression
post-transcriptionally either via the degradation of target mRNAs or the inhibition of protein …