Role of microRNAs, circRNAs and long noncoding RNAs in acute myeloid leukemia
Acute myeloid leukemia (AML) is a malignant tumor of the immature myeloid hematopoietic
cells in the bone marrow (BM). It is a highly heterogeneous disease, with rising morbidity …
cells in the bone marrow (BM). It is a highly heterogeneous disease, with rising morbidity …
Regulation of the MIR155 host gene in physiological and pathological processes
TS Elton, H Selemon, SM Elton, NL Parinandi - Gene, 2013 - Elsevier
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
Cancer Genome Atlas Research … - New England Journal of …, 2013 - Mass Medical Soc
Background Many mutations that contribute to the pathogenesis of acute myeloid leukemia
(AML) are undefined. The relationships between patterns of mutations and epigenetic …
(AML) are undefined. The relationships between patterns of mutations and epigenetic …
Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
V Neudecker, M Haneklaus, O Jensen… - Journal of Experimental …, 2017 - rupress.org
MicroRNA (miRNA)-mediated RNA interference regulates many immune processes, but how
miRNA circuits orchestrate aberrant intestinal inflammation during inflammatory bowel …
miRNA circuits orchestrate aberrant intestinal inflammation during inflammatory bowel …
miR‐223: infection, inflammation and cancer
M Haneklaus, M Gerlic, LAJ O'Neill… - Journal of internal …, 2013 - Wiley Online Library
Expression of the micro RNA miR‐223 is deregulated during influenza or hepatitis B
infection and in inflammatory bowel disease, type 2 diabetes, leukaemia and lymphoma …
infection and in inflammatory bowel disease, type 2 diabetes, leukaemia and lymphoma …
Haemolysis during sample preparation alters microRNA content of plasma
The presence of cell-free microRNAs (miRNAs) has been detected in a range of body fluids.
The miRNA content of plasma/serum in particular has been proposed as a potential source …
The miRNA content of plasma/serum in particular has been proposed as a potential source …
The impact of hemolysis on cell-free microRNA biomarkers
MB Kirschner, JJB Edelman, SCH Kao… - Frontiers in …, 2013 - frontiersin.org
Cell-free microRNAs in plasma and serum have become a promising source of biomarkers
for various diseases. Despite rapid progress in this field, there remains a lack of consensus …
for various diseases. Despite rapid progress in this field, there remains a lack of consensus …
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in Eμ-miR155 transgenic mice
MicroRNAs (miRNAs) represent a newly discovered class of posttranscriptional regulatory
noncoding small RNAs that bind to targeted mRNAs and either block their translation or …
noncoding small RNAs that bind to targeted mRNAs and either block their translation or …
A potential role of microvesicle-containing miR-223/142 in lung inflammation
Background Uncontrolled lung inflammation is one of the prominent features in the
pathogenesis of lung infection-associated acute lung injury (ALI). Microvesicles (MVs) are …
pathogenesis of lung infection-associated acute lung injury (ALI). Microvesicles (MVs) are …
MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death
R Schickel, B Boyerinas, SM Park, ME Peter - Oncogene, 2008 - nature.com
Micro (mi) RNAs are small, highly conserved noncoding RNAs that control gene expression
post-transcriptionally either via the degradation of target mRNAs or the inhibition of protein …
post-transcriptionally either via the degradation of target mRNAs or the inhibition of protein …