Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease that encompasses a
spectrum of pathological conditions, ranging from simple steatosis (NAFL), nonalcoholic …

Despite tremendous research advancements in nonalcoholic fatty liver disease (NAFLD),
our understanding of sex differences in NAFLD remains insufficient. This review summarizes …

Background & Aims Endothelial dysfunction plays an essential role in liver injury, yet the
phenotypic regulation of liver sinusoidal endothelial cells (LSECs) remains unknown …

The aim of this review is to give an outline of the blood clearance function of the liver
sinusoidal endothelial cells (LSECs) in health and disease. Lining the hundreds of millions …

Capillarization, lack of liver sinusoidal endothelial cell (LSEC) fenestration, and formation of
an organized basement membrane not only precedes fibrosis, but is also permissive for …

Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the
progression of chronic cholestatic liver diseases. We previously reported that cholangiocyte …

Background & Aims Angiocrine signaling by liver sinusoidal endothelial cells (LSECs)
regulates hepatic functions such as growth, metabolic maturation, and regeneration …

BACKGROUND & AIMS: Capillarization, characterized by loss of differentiation of liver
sinusoidal endothelial cells (LSECs), precedes the onset of hepatic fibrosis. We investigated …

The liver sinusoidal endothelial cell (LSEC) forms the fenestrated wall of the hepatic
sinusoid and functions as a control post regulating and surveying the trafficking of molecules …