Stroke is one of the leading causes of death and long-term disability worldwide. More than
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …

Mitochondria are double-membrane organelles that provide the majority of a cell's energy.
Furthermore, mitochondria are involved in various cellular biological activities, including …

Our previous study has proved that down-regulation of CLDN10 (Claudin-10) in ccRCC
(clear cell renal cell carcinoma) was closely related to tumor metastasis and predicted an …

Heart failure is the final stage of various cardiovascular diseases and seriously threatens
human health. Increasing mediators have been found to be involved in the pathogenesis of …

Abstract Mitochondrial calcium ([Ca 2+] m) overload is considered a major trigger of
cardiomyocyte death during myocardial ischemia/reperfusion (I/R) injury. Grpel2 is located …

Abstract Claudin-5 (CLDN5) is an essential component of tight junctions (TJs) and is critical
for the integrity of the blood-brain barrier (BBB), ensuring homeostasis and protection from …

This study aims to investigate the role of claudin-5 (Cldn5) in cardiac structural integrity.
Proteomic analysis was performed to screen the protein profiles in enlarged left atrium from …

Irisin is protective in the cardiac microenvironment and can resist doxorubicin-induced
cardiotoxicity. The purpose of this study was to investigate the connection between Irisin …

Background: Although it is critically important to understand the underlying molecular and
electrophysiological changes that predispose to the induction and maintenance of atrial …

Резюме Гипоксическое кондиционирование заняло важное место в спектре
немедикаментозных методов стимуляции адаптационного потенциала здорового …