The field of new psychoactive substances (NPS) is highly dynamic and the situation
changes from year to year. Therefore, the current review provides a timely update about the …

Therapeutic Drug monitoring (TDM) is a multidisciplinary endeavor encompassing skills of
the laboratory, clinical pharmacologists and physicians aimed at providing the best possible …

Small molecules containing carboxylic acid functional groups are ubiquitous throughout
biology, playing vital roles in biological chemistry ranging from energy metabolism to cellular …

Targeted metabolite analysis in combination with 13 C-tracing is a convenient strategy to
determine pathway activity in biological systems; however, metabolite analysis is limited by …

The artificial increase of the physical capability of horses using drugs is well known in racing
and other equine sports. Both illicit and therapeutic substances are regarded as prohibited …

Background: Significant advances have been occurred in analytical research since the
1970s by Liquid Chromatography (LC) as the separation method. Reverse Phase Liquid …

Introduction: The identification and characterization of the metabolites during the early
stages of discovery and development of new drug candidates are essential to establish the …

Accurate and reliable quantification of organic acids with carboxylic acid functional groups in
complex biological samples remains a major analytical challenge in clinical chemistry …

Colistin is an old antibiotic reintroduced in response to an increased incidence of multi-
resistant Gram-negative bacterial infections. It has a narrow therapeutic window, and dose …

Aim: Fructose and sorbitol are utilized as biomarkers for nonalcoholic steatohepatitis.
Measurement of fructose and sorbitol levels helps understanding disease progression, drug …