Interneuron types as attractors and controllers

G Fishell, A Kepecs - Annual review of neuroscience, 2020 - annualreviews.org
Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …

MicroRNAs instruct and maintain cell type diversity in the nervous system

N Zolboot, JX Du, F Zampa, G Lippi - Frontiers in Molecular …, 2021 - frontiersin.org
Characterizing the diverse cell types that make up the nervous system is essential for
understanding how the nervous system is structured and ultimately how it functions. The …

Early somatostatin interneuron connectivity mediates the maturation of deep layer cortical circuits

SN Tuncdemir, B Wamsley, FJ Stam, F Osakada… - Neuron, 2016 - cell.com
The precise connectivity of somatostatin and parvalbumin cortical interneurons is generated
during development. An understanding of how these interneuron classes incorporate into …

Activity regulates cell death within cortical interneurons through a calcineurin-dependent mechanism

R Priya, MF Paredes, T Karayannis, N Yusuf, X Liu… - Cell reports, 2018 - cell.com
We demonstrate that cortical interneurons derived from ventral eminences, including the
caudal ganglionic eminence, undergo programmed cell death. Moreover, with the exception …

Thyroid hormone, gene expression, and central nervous system: where we are

G Giannocco, MML Kizys, RM Maciel… - Seminars in Cell & …, 2021 - Elsevier
Thyroid hormones (TH; T3 and T4) play a fundamental role in the fetal stage to the adult
phase, controlling gene and protein expression in virtually all tissues. The endocrine and …

microRNA-dependent regulation of gene expression in GABAergic interneurons

KA Kołosowska, G Schratt, J Winterer - Frontiers in Cellular …, 2023 - frontiersin.org
Information processing within neuronal circuits relies on their proper development and a
balanced interplay between principal and local inhibitory interneurons within those circuits …

Crosstalk between intracellular and extracellular signals regulating interneuron production, migration and integration into the cortex

E Peyre, CG Silva, L Nguyen - Frontiers in cellular neuroscience, 2015 - frontiersin.org
During embryogenesis, cortical interneurons are generated by ventral progenitors located in
the ganglionic eminences of the telencephalon. They travel along multiple tangential paths …

MicroRNA-138 controls hippocampal interneuron function and short-term memory in mice

R Daswani, C Gilardi, M Soutschek, P Nanda, K Weiss… - Elife, 2022 - elifesciences.org
The proper development and function of neuronal circuits rely on a tightly regulated balance
between excitatory and inhibitory (E/I) synaptic transmission, and disrupting this balance can …

MicroRNA-218 instructs proper assembly of hippocampal networks

SR Taylor, M Kobayashi, A Vilella, D Tiwari, N Zolboot… - Elife, 2023 - elifesciences.org
The assembly of the mammalian brain is orchestrated by temporally coordinated waves of
gene expression. Post-transcriptional regulation by microRNAs (miRNAs) is a key aspect of …

Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons

Z Kounoupa, S Tivodar, K Theodorakis… - Journal of Cell …, 2023 - journals.biologists.com
ABSTRACT Rho GTPases, among them Rac1 and Rac3, are major transducers of
extracellular signals and are involved in multiple cellular processes. In cortical interneurons …