Interneuron types as attractors and controllers
Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …
challenging us to appropriately classify them. We previously suggested that interneuron …
MicroRNAs instruct and maintain cell type diversity in the nervous system
Characterizing the diverse cell types that make up the nervous system is essential for
understanding how the nervous system is structured and ultimately how it functions. The …
understanding how the nervous system is structured and ultimately how it functions. The …
Early somatostatin interneuron connectivity mediates the maturation of deep layer cortical circuits
The precise connectivity of somatostatin and parvalbumin cortical interneurons is generated
during development. An understanding of how these interneuron classes incorporate into …
during development. An understanding of how these interneuron classes incorporate into …
Activity regulates cell death within cortical interneurons through a calcineurin-dependent mechanism
We demonstrate that cortical interneurons derived from ventral eminences, including the
caudal ganglionic eminence, undergo programmed cell death. Moreover, with the exception …
caudal ganglionic eminence, undergo programmed cell death. Moreover, with the exception …
Thyroid hormone, gene expression, and central nervous system: where we are
G Giannocco, MML Kizys, RM Maciel… - Seminars in Cell & …, 2021 - Elsevier
Thyroid hormones (TH; T3 and T4) play a fundamental role in the fetal stage to the adult
phase, controlling gene and protein expression in virtually all tissues. The endocrine and …
phase, controlling gene and protein expression in virtually all tissues. The endocrine and …
microRNA-dependent regulation of gene expression in GABAergic interneurons
KA Kołosowska, G Schratt, J Winterer - Frontiers in Cellular …, 2023 - frontiersin.org
Information processing within neuronal circuits relies on their proper development and a
balanced interplay between principal and local inhibitory interneurons within those circuits …
balanced interplay between principal and local inhibitory interneurons within those circuits …
Crosstalk between intracellular and extracellular signals regulating interneuron production, migration and integration into the cortex
During embryogenesis, cortical interneurons are generated by ventral progenitors located in
the ganglionic eminences of the telencephalon. They travel along multiple tangential paths …
the ganglionic eminences of the telencephalon. They travel along multiple tangential paths …
MicroRNA-138 controls hippocampal interneuron function and short-term memory in mice
R Daswani, C Gilardi, M Soutschek, P Nanda, K Weiss… - Elife, 2022 - elifesciences.org
The proper development and function of neuronal circuits rely on a tightly regulated balance
between excitatory and inhibitory (E/I) synaptic transmission, and disrupting this balance can …
between excitatory and inhibitory (E/I) synaptic transmission, and disrupting this balance can …
MicroRNA-218 instructs proper assembly of hippocampal networks
The assembly of the mammalian brain is orchestrated by temporally coordinated waves of
gene expression. Post-transcriptional regulation by microRNAs (miRNAs) is a key aspect of …
gene expression. Post-transcriptional regulation by microRNAs (miRNAs) is a key aspect of …
Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons
Z Kounoupa, S Tivodar, K Theodorakis… - Journal of Cell …, 2023 - journals.biologists.com
ABSTRACT Rho GTPases, among them Rac1 and Rac3, are major transducers of
extracellular signals and are involved in multiple cellular processes. In cortical interneurons …
extracellular signals and are involved in multiple cellular processes. In cortical interneurons …