Liposomes are now in the marketplace as cosmeticeuticals and, more important,
pharmaceuticals. Three major achievements of liposome application: steric stabilization …

Cationic lipid-mediated nucleic acid and protein delivery is becoming increasingly popular
for in vitro and in vivo applications. While the chemistry of cationic lipid carriers is moving …

Lipid nanoparticles (LNPs) have shown remarkable success in delivering genetic materials
like COVID-19 LNP vaccines, such as mRNA-1273/SpikeVax by Moderna and …

Solid lipid nanoparticles (SLNs) have been proposed in the 1990s as appropriate drug
delivery systems, and ever since they have been applied in a wide variety of cosmetic and …

Alkylammonium binding to DNA was studied by isothermal titration calorimetry.
Experimental data, obtained as functions of alkyl chain length, salt concentration, DNA …

In this perspective article, we focus on recent developments in the theory of charge effects in
biological DNA-related systems. The electrostatic effects on different levels of DNA …

Cancer is an extremely complex disease, typically caused by mutations in cancer-critical
genes. By delivering therapeutic nucleic acids (NAs) to patients, gene therapy offers the …

Mechanisms of cationic lipid-based nucleic acid delivery are receiving increasing attention,
but despite this the factors that determine high or low activity of lipoplexes are poorly …

Osmolytes are a class of compounds ubiquitously used by living organisms to respond to
cellular stress or to fine-tune molecular properties in the cell. These compounds are also …

The adsorption free energy of charged proteins on mixed membranes, containing varying
amounts of (oppositely) charged lipids, is calculated based on a mean-field free energy …