Chemodynamic therapy (CDT), a novel cancer therapeutic strategy defined as the treatment
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …

Nanodynamic therapies that generate free radicals/reactive oxygen species (ROS) in situ
have the possibility to treat deep-seated tumors and have gradually become attractive …

Vitamin C (L-ascorbic acid) has been known as an antioxidant for most people. However, its
physiological role is much larger and encompasses very different processes ranging from …

Oxidative stress is a phenomenon caused by an imbalance between production and
accumulation of oxygen reactive species (ROS) in cells and tissues and the ability of a …

Background Many nutrients have powerful immunomodulatory actions with the potential to
alter susceptibility to coronavirus disease 2019 (COVID-19) infection, progression to …

The pharmacokinetics of vitamin C (vitC) is indeed complex. Regulated primarily by a family
of saturable sodium dependent vitC transporters (SVCTs), the absorption and elimination …

Over the past century, the notion that vitamin C can be used to treat cancer has generated
much controversy. However, new knowledge regarding the pharmacokinetic properties of …

Heavy metals and metalloid exposure are among the most common factors responsible for
reproductive toxicity in human beings. Several studies have indicated that numerous metals …

Vitamin C (Ascorbic Acid), the antiscorbutic vitamin, cannot be synthesized by humans and
other primates, and has to be obtained from diet. Ascorbic acid is an electron donor and acts …

Pharmacological ascorbate has been proposed as a potential anti-cancer agent when
combined with radiation and chemotherapy. The anti-cancer effects of ascorbate are …