Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

Invasive Candida infections remain an important cause of morbidity and mortality, especially
in hospitalized and immunocompromised or critically ill patients. A limited number of …

Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …

Despite improvement of antifungal therapies over the last 30 years, the phenomenon of
antifungal resistance is still of major concern in clinical practice. In the last 10 years the …

Background Candida auris is a multidrug-resistant yeast associated with hospital outbreaks
worldwide. During 2015–2016, multiple outbreaks were reported in Colombia. We aimed to …

Ergosterol (ERG) is a critical sterol in the cell membranes of fungi, and its biosynthesis is
tightly regulated by 25 known enzymes along the ERG production pathway. The effects of …

The fungal pathogen Candida glabrata has emerged as a major health threat since it readily
acquires resistance to multiple drug classes, including triazoles and/or echinocandins. Thus …

Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and
vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous …

We checked all papers published along the last 10 years describing epidemiological,
diagnostic, and clinical aspects of infections by MDR Candida spp., with emphasis on C …

The evolution of drug resistance in microbial pathogens provides a paradigm for
investigating evolutionary dynamics with important consequences for human health …