Nutraceuticals and cancer: Potential for natural polyphenols

J Maiuolo, M Gliozzi, C Carresi, V Musolino… - Nutrients, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, associated with multifactorial
pathophysiological components. In particular, genetic mutations, infection or inflammation …

Curcumin combination chemotherapy: The implication and efficacy in cancer

BL Tan, ME Norhaizan - Molecules, 2019 - mdpi.com
Many chemotherapeutic drugs have been used for the treatment of cancer, for instance,
doxorubicin, irinotecan, 5-fluorouracil, cisplatin, and paclitaxel. However, the effectiveness of …

[HTML][HTML] Moringa oleifera and their phytonanoparticles: Potential antiproliferative agents against cancer

C Tiloke, K Anand, RM Gengan… - Biomedicine & …, 2018 - Elsevier
Cancer is classified as one of the leading causes of global mortality. It has affected millions
of people, often with poor prognosis. Having severe side-effects with conventional …

Mushroom-derived indole alkaloids

JA Homer, J Sperry - Journal of natural products, 2017 - ACS Publications
Mushroom-Derived Indole Alkaloids | Journal of Natural Products ACS ACS Publications C&EN
CAS Find my institution Log In Journal of Natural Products ACS Publications. Most Trusted. Most …

Natural products for pancreatic cancer treatment: From traditional medicine to modern drug discovery

A Kim, J Ha, J Kim, Y Cho, J Ahn, C Cheon, SH Kim… - Nutrients, 2021 - mdpi.com
Pancreatic cancer, the seventh most lethal cancer around the world, is considered
complicated cancer due to poor prognosis and difficulty in treatment. Despite all the …

Alpinumisoflavone suppresses hepatocellular carcinoma cell growth and metastasis via NLRP3 inflammasome-mediated pyroptosis

Y Zhang, H Yang, M Sun, T He, Y Liu, X Yang… - Pharmacological …, 2020 - Springer
Aim This research aims to explore the effect of alpinumisoflavone (AIF) as an anti-cancer
drug for the treatment of patients with hepatocellular carcinoma (HCC). Methods Cell …

Neuroprotective potential of berberine against doxorubicin-induced toxicity in rat's brain

G Ibrahim Fouad, KA Ahmed - Neurochemical Research, 2021 - Springer
Chemotherapy-associated neurotoxicity is one of the principal side-effects for doxorubicin
(DOX)-treated cancer patients. Despite its poor-penetration across the blood–brain barrier …

Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)

G Xia, H Wang, Z Song, Q Meng, X Huang… - Journal of Experimental & …, 2017 - Springer
Background Pancreatic cancer is susceptible to gemcitabine resistance, and patients
receive less benefit from gemcitabine chemotherapy. Previous studies report that gambogic …

Berberine overcomes gemcitabine-associated chemoresistance through regulation of Rap1/PI3K-Akt signaling in pancreatic ductal adenocarcinoma

K Okuno, C Xu, S Pascual-Sabater, M Tokunaga… - Pharmaceuticals, 2022 - mdpi.com
Gemcitabine (Gem)-based chemotherapy is one of the first-line treatments for pancreatic
ductal adenocarcinoma (PDAC). However, its clinical effect is limited due to development of …

Pancreatic cancer and therapy: role and regulation of cancer stem cells

S Barman, I Fatima, AB Singh, P Dhawan - International journal of …, 2021 - mdpi.com
Despite significant improvements in clinical management, pancreatic cancer (PC) remains
one of the deadliest cancer types, as it is prone to late detection with extreme metastatic …