Parkinson's disease (PD) is one of most disabling disorders of the central nervous system.
The motor symptoms of Parkinson's disease: shaking, rigidity, slowness of movement …

Background Major depressive disorder (MDD) is highly debilitating, difficult to treat, has a
high rate of recurrence, and negatively impacts the individual and society as a whole. One …

Remote health assessments that gather real-world data (RWD) outside clinic settings
require a clear understanding of appropriate methods for data collection, quality …

Parkinson's disease has a long prodromal stage with various subclinical motor and non-
motor manifestations; however, their evolution in the years before Parkinson's disease is …

Background: Ubiquitous digital technologies such as smartphone sensors promise to
fundamentally change biomedical research and treatment monitoring in neurological …

Background Remote, non-invasive and objective tests that can be used to support expert
diagnosis for Parkinson's disease (PD) are lacking. Methods Participants underwent …

A suite of components comprising an objective measurement medical data collection device
and a cohort database may standardize, simplify, and objectify clinical outcomes tracking …

The unmet timely diagnosis requirements, that take place years after substantial neural loss
and neuroperturbations in neuropsychiatric disorders, affirm the dire need for biomarkers …

Producing accurate movements may rely on the functional independence of sensorimotor
circuits within basal ganglia nuclei. In parkinsonism there is abnormal synchrony of electrical …

Power spectra from local field potentials (LFPs) recorded post-operatively from the deep
brain stimulation (DBS) macroelectrode show prominence of the beta rhythm (11–30 Hz) in …