Non-alcoholic fatty liver disease (NAFLD): a review of pathophysiology, clinical management and effects of weight loss

S Pouwels, N Sakran, Y Graham, A Leal, T Pintar… - BMC endocrine …, 2022 - Springer
Given the increasing prevalence of diabetes and obesity worldwide, the deleterious effects
of non-alcoholic fatty liver disease (NAFLD) are becoming a growing challenge for public …

Role of oxidative stress in the pathogenesis of non-alcoholic fatty liver disease: implications for prevention and therapy

JC Arroyave-Ospina, Z Wu, Y Geng, H Moshage - Antioxidants, 2021 - mdpi.com
Oxidative stress (OxS) is considered a major factor in the pathophysiology of inflammatory
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …

Role of intestinal microbiota in the bioavailability and physiological functions of dietary polyphenols

K Kawabata, Y Yoshioka, J Terao - Molecules, 2019 - mdpi.com
Polyphenols are categorized as plant secondary metabolites, and they have attracted much
attention in relation to human health and the prevention of chronic diseases. In recent years …

Whole grain benefit: Synergistic effect of oat phenolic compounds and β-glucan on hyperlipidemia via gut microbiota in high-fat-diet mice

Y Li, C Qin, L Dong, X Zhang, Z Wu, L Liu, J Yang… - Food & Function, 2022 - pubs.rsc.org
Increasing evidence has confirmed that whole grain oats are effective in regulating
hyperlipidemia. However, which specific ingredient is crucial remains unclear. This study …

Polyphenols in metabolic diseases

A Gasmi, PK Mujawdiya, S Noor, R Lysiuk… - Molecules, 2022 - mdpi.com
Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or
more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic …

Curcumin, quercetin, catechins and metabolic diseases: The role of gut microbiota

U Shabbir, M Rubab, EBM Daliri, R Chelliah, A Javed… - Nutrients, 2021 - mdpi.com
Polyphenols (PPs) are the naturally occurring bioactive components in fruits and vegetables,
and they are the most abundant antioxidant in the human diet. Studies are suggesting that …

A mechanistic review of the anticancer potential of hesperidin, a natural flavonoid from citrus fruits

P Pandey, F Khan - Nutrition Research, 2021 - Elsevier
Hesperidin, a phytoactive compound, is an abundant and economical dietary bioflavonoid
possessing numerous biological and medicinal benefits. Several studies have strongly …

Nonalcoholic fatty liver disease

JM Clark, FL Brancati, AM Diehl - Gastroenterology, 2002 - Elsevier
cohol-induced liver disease but develops in individuals who are not heavy drinkers. NAFLD
is likely to be the most common cause of chronic liver disease in many countries and may …

[HTML][HTML] Managing obesity through natural polyphenols: A review

M Singh, T Thrimawithana, R Shukla, B Adhikari - Future Foods, 2020 - Elsevier
Obesity is a pervasive global health problem needing urgent research and regulatory
attention. Although synthetic anti-obesity drugs are available, they come with considerable …

Ashwagandha (Withania somnifera) root extract attenuates hepatic and cognitive deficits in thioacetamide-induced rat model of hepatic encephalopathy via induction …

HMA Khalil, HA Eliwa, RA El-Shiekh… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Ashwagandha (ASH) is one of the medicinal plants used
in traditional Indian, Ayurvedic, and Unani medicines for their broad range of …