Molecular mechanism of microbiota metabolites in preterm birth: pathological and therapeutic insights
AZ Ansari, S Bose, Y You, S Park, Y Kim - International Journal of …, 2021 - mdpi.com
Preterm birth (PTB) refers to the birth of infants before 37 weeks of gestation and is a
challenging issue worldwide. Evidence reveals that PTB is a multifactorial dysregulation …
challenging issue worldwide. Evidence reveals that PTB is a multifactorial dysregulation …
[HTML][HTML] The efficacy of emergency cervical cerclage in singleton and twin pregnancies: a systematic review with meta-analysis
CC Hulshoff, RP Bosgraaf, MEA Spaanderman… - American Journal of …, 2023 - Elsevier
OBJECTIVE An emergency (rescue) cervical cerclage can be offered to pregnant women
presenting with dilatation and prolapsed membranes in the second trimester of pregnancy …
presenting with dilatation and prolapsed membranes in the second trimester of pregnancy …
The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies
N Gomez‐Lopez, R Romero, Y Xu… - American Journal of …, 2018 - Wiley Online Library
Problem The immune cellular composition of amniotic fluid is poorly understood. Herein, we
determined: 1) the immunophenotype of amniotic fluid immune cells during the second and …
determined: 1) the immunophenotype of amniotic fluid immune cells during the second and …
Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor
Objective Amniotic fluid cytokines have been implicated in the mechanisms of preterm labor
and birth. Cytokines can be packaged within or on the surface of extracellular vesicles. The …
and birth. Cytokines can be packaged within or on the surface of extracellular vesicles. The …
[HTML][HTML] Cervicovaginal fluid cytokines as predictive markers of preterm birth in symptomatic women
S Park, YA You, H Yun, SJ Choi… - Obstetrics & …, 2020 - synapse.koreamed.org
Objective Here, we investigated whether cytokines in the cervicovaginal fluid (CVF) can be
predictive markers of preterm birth (PTB). Methods A multi-center prospective cohort study …
predictive markers of preterm birth (PTB). Methods A multi-center prospective cohort study …
Does the amniotic fluid of mice contain a viable microbiota?
The existence of an amniotic fluid microbiota (ie, a viable microbial community) in mammals
is controversial. Its existence would require a fundamental reconsideration of fetal in utero …
is controversial. Its existence would require a fundamental reconsideration of fetal in utero …
Amniotic fluid neutrophils can phagocytize bacteria: A mechanism for microbial killing in the amniotic cavity
N Gomez‐Lopez, R Romero… - American journal of …, 2017 - Wiley Online Library
Problem Neutrophils are capable of performing phagocytosis, a primary mechanism for
microbial killing. Intra‐amniotic infection is characterized by an influx of neutrophils into the …
microbial killing. Intra‐amniotic infection is characterized by an influx of neutrophils into the …
Inflammation-induced adverse pregnancy and neonatal outcomes can be improved by the immunomodulatory peptide exendin-4
Preterm birth is the leading cause of neonatal morbidity and mortality worldwide.
Inflammation is causally linked to preterm birth; therefore, finding an intervention that …
Inflammation is causally linked to preterm birth; therefore, finding an intervention that …
Human β‐defensin‐1: A natural antimicrobial peptide present in amniotic fluid that is increased in spontaneous preterm labor with intra‐amniotic infection
A Varrey, R Romero, B Panaitescu… - American journal of …, 2018 - Wiley Online Library
Problem Human β‐defensins (HBD s) are antimicrobial peptides that participate in the
soluble innate immune mechanisms against infection. Herein, we determined whether HBD …
soluble innate immune mechanisms against infection. Herein, we determined whether HBD …
Human β-defensin-3 participates in intra-amniotic host defense in women with labor at term, spontaneous preterm labor and intact membranes, and preterm prelabor …
Abstract Objective: Human β-defensin-3 (HBD-3) has a broad spectrum of antimicrobial
activity, and activity and, therefore, plays a central role in host defense mechanisms against …
activity, and activity and, therefore, plays a central role in host defense mechanisms against …