Background Suboptimal exposure to antituberculosis (anti-TB) drugs has been associated
with unfavourable treatment outcomes. We aimed to investigate estimates and determinants …

There has been an increased interest in pharmacokinetics and pharmacodynamics (PKPD)
of anti-tuberculosis drugs. A better understanding of the relationship between drug …

Background Rifampin-resistant tuberculosis is a leading cause of morbidity worldwide; only
one-third of persons start treatment, and outcomes are often inadequate. Several trials …

BACKGROUND: Adverse effects (AE) to TB treatment cause morbidity, mortality and
treatment interruption. The aim of these clinical standards is to encourage best practise for …

Introduction: No previous systematic reviews have comprehensively investigated the
features of Xpert MTB/XDR and other rapid tests to diagnose pre-XDR/XDR-TB. The aim of …

Background Rifampin-resistant tuberculosis is a leading cause of morbidity worldwide; only
one-third of persons initiate treatment and outcomes are often inadequate. Several trials …

BACKGROUND: These clinical standards aim to provide guidance for diagnosis, treatment,
and management of drug-susceptible TB in children and adolescents. METHODS: Fifty-two …

Abstract Background and Objective Quantifying exposure to drugs for personalized dose
adjustment is of critical importance in patients with tuberculosis who may be at risk of …

BACKGROUND: The aim of these clinical standards is to provide guidance on 'best
practice'care for the diagnosis, treatment and prevention of post-COVID-19 lung disease …

Abstract Background Mycobacterium tuberculosis (Mtb) has been found to persist within
cavities in patients who have completed their anti-tuberculosis therapy. The clinical …