[PDF][PDF] Sjögren's syndrome: one year in review 2022

V Manfrè, LG Chatzis, G Cafaro, S Fonzetti… - Clin Exp …, 2022 - clinexprheumatol.org
Primary Sjögren's syndrome (pSS) is a complex disabling systemic autoimmune disorder.
The hallmark of pSS is the T-cell-mediated hyperactivation of B-cells, evolving from …

Epidemiology of Sjögren syndrome

M Beydon, S McCoy, Y Nguyen, T Sumida… - Nature Reviews …, 2024 - nature.com
Sjögren syndrome is a phenotypically varied autoimmune disorder that can occur alone in
primary Sjögren syndrome or in association with other connective tissue diseases (CTDs) …

Is minor salivary gland biopsy still mandatory in Sjogren's syndrome? Does seronegative Sjogren's syndrome exist?

C Baldini, O Berardicurti, R Giacomelli… - Autoimmunity …, 2023 - Elsevier
Sjӧgren's disease (SjD) is a systemic autoimmune disorder characterized by the chronic
inflammation and dysfunction of exocrine glands, mainly salivary glands, causing dryness of …

Sjögren's syndrome

F André, BC Böckle - JDDG: Journal der Deutschen …, 2022 - Wiley Online Library
Sjögren's syndrome (SjS) is an autoimmune disease characterized by the triad of sicca
symptoms, fatigue and pain. This diagnosis is usually made in women at the average age of …

Clinical picture, outcome and predictive factors of lymphoma in primary Sjögren's syndrome: results from a harmonized dataset (1981–2021)

LG Chatzis, IE Stergiou, AV Goules, V Pezoulas… - …, 2022 - academic.oup.com
Abstract Objectives Primary Sjögren's Syndrome (pSS) carries the highest risk for non-
Hodgkin's lymphoma (NHL) development among systemic autoimmune diseases. However …

[PDF][PDF] Systemic vasculitis: one year in review 2022

G La Rocca, G Del Frate, P Delvino… - Clin Exp …, 2022 - clinexprheumatol.org
Systemic vasculitis are rare heterogeneous disorders potentially involving any organ and
system with a relevant burden of mortality and comorbidity. As in the previous annual …

Cancer incidence in primary Sjögren's syndrome: Data from the French hospitalization database

R Goulabchand, N Malafaye, W Jacot, PWD Viel… - Autoimmunity …, 2021 - Elsevier
The relationship between cancer and primary Sjögren's syndrome (pSS) is uncertain. While
the increased risk of hematological malignancies is well-known, data on the comparative …

Sjögren syndrome: looking forward to the future

S Zandonella Callegher, I Giovannini… - Therapeutic …, 2022 - journals.sagepub.com
Primary Sjögren's syndrome (pSS) is a heterogeneous disease characterised by a wide
spectrum of manifestations that vary according to the different stages of the disease and …

[HTML][HTML] Addressing the clinical unmet needs in primary Sjögren's Syndrome through the sharing, harmonization and federated analysis of 21 European cohorts

VC Pezoulas, A Goules, F Kalatzis, L Chatzis… - Computational and …, 2022 - Elsevier
For many decades, the clinical unmet needs of primary Sjögren's Syndrome (pSS) have
been left unresolved due to the rareness of the disease and the complexity of the underlying …

Why do drug treatments fail in Sjögren's disease? Considerations for treatment, trial design and interpretation of clinical efficacy

S Arends, GM Verstappen, L de Wolff… - Expert review of …, 2023 - Taylor & Francis
Introduction Despite ongoing efforts to develop effective therapeutics, no disease-modifying
drugs have been officially licensed for the indication of Sjögren's disease (SjD). This is partly …