Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …

Drug discovery is based on bioactivity screening of natural sources, traditionally represented
by bacteria fungi and plants. Bioactive natural products and their secondary metabolites …

Abstract The Integrated Microbial Genomes & Microbiomes system (IMG/M: https://img. jgi.
doe. gov/m/) at the Department of Energy (DOE) Joint Genome Institute (JGI) continues to …

Abstract The Integrated Microbial Genomes & Microbiomes system (IMG/M: https://img. jgi.
doe. gov/m/) contains annotated isolate genome and metagenome datasets sequenced at …

Fueled by the explosion of (meta) genomic data, genome mining of specialized metabolites
has become a major technology for drug discovery and studying microbiome ecology. In …

Abstract The Integrated Microbial Genomes & Microbiomes system v. 5.0 (IMG/M: https://img.
jgi. doe. gov/m/) contains annotated datasets categorized into: archaea, bacteria, eukarya …

Fungi produce several bioactive metabolites, pigments, dyes, antioxidants, polysaccharides,
and industrial enzymes. Fungal products are also the primary sources of functional food and …

Engineering microbial cells to efficiently synthesize high-value-added natural products has
received increasing attention in recent years. In this review, we describe the pipeline to build …

Antibiotic resistance is a global problem which affects human health. The imprudent use of
antibiotics (medicine, agriculture, aquaculture, and food industry) has resulted in the broader …

Microbial secondary metabolism is a reservoir of bioactive compounds of immense
biotechnological and biomedical potential. The biosynthetic machinery responsible for the …