Epicardial adipose tissue in contemporary cardiology

G Iacobellis - Nature reviews cardiology, 2022 - nature.com
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …

Epicardial adipose tissue and cardiovascular diseases

AM Ansaldo, F Montecucco, A Sahebkar… - International journal of …, 2019 - Elsevier
Obesity is a heterogeneous disease with different degrees of cardiovascular (CV) and
metabolic manifestations. Certain ectopic fat depots may contribute to obesity-related CV …

The molecular mechanisms of obesity paradox

AS Antonopoulos, D Tousoulis - Cardiovascular research, 2017 - academic.oup.com
Clinical observations suggest a complex relationship between human obesity and
cardiovascular disease. Whilst abdominal (visceral) adiposity leads to deleterious metabolic …

Impact of different ectopic fat depots on cardiovascular and metabolic diseases

D Ferrara, F Montecucco, F Dallegri… - Journal of cellular …, 2019 - Wiley Online Library
A growing body of evidence is pointing out the pathophysiological role of fat accumulation in
different organs. Ectopic fat depots within heart, liver, skeletal muscle, kidney, and pancreas …

Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease

VB Patel, S Shah, S Verma, GY Oudit - Heart failure reviews, 2017 - Springer
Obesity and diabetes are strongly associated with metabolic and cardiovascular disorders
including dyslipidemia, coronary artery disease, hypertension, and heart failure. Adipose …

Regulation of visceral and epicardial adipose tissue for preventing cardiovascular injuries associated to obesity and diabetes

N González, Z Moreno-Villegas… - Cardiovascular …, 2017 - Springer
Nowadays, obesity is seriously increasing in most of the populations all over the world, and
is associated with the development and progression of high-mortality diseases such as type …

Effects of dapagliflozin on human epicardial adipose tissue: modulation of insulin resistance, inflammatory chemokine production, and differentiation ability

E Díaz-Rodríguez, RM Agra… - Cardiovascular …, 2018 - academic.oup.com
Aims In patients with cardiovascular disease, epicardial adipose tissue (EAT) is
characterized by insulin resistance, high pro-inflammatory chemokines, and low …

Adipokines from white adipose tissue in regulation of whole body energy homeostasis

B Sahu, NC Bal - Biochimie, 2023 - Elsevier
Diseases originating from altered energy homeostasis including obesity, and type 2
diabetes are rapidly increasing worldwide. Research in the last few decades on animal …

The role of epicardial adipose tissue in cardiac biology: classic concepts and emerging roles

AS Antonopoulos, C Antoniades - The Journal of physiology, 2017 - Wiley Online Library
Classic concepts about the role of epicardial adipose tissue (EpAT) in heart physiology
include its role in cardiac metabolism, mechanical protection of coronaries, innervation and …

Role of epicardial adipose tissue in health and disease: a matter of fat?

B Gaborit, C Sengenes, P Ancel, A Jacquier… - Comprehensive …, 2017 - hal.science
Epicardial adipose tissue (EAT) is a small but very biologically active ectopic fat depot that
surrounds the heart. Given its rapid metabolism, thermogenic capacity, unique …