Bacteriophage-based biomaterials for tissue regeneration

B Cao, Y Li, T Yang, Q Bao, M Yang, C Mao - Advanced drug delivery …, 2019 - Elsevier
Bacteriophage, also called phage, is a human-safe bacteria-specific virus. It is a
monodisperse biological nanostructure made of proteins (forming the outside surface) and …

Virus-incorporated biomimetic nanocomposites for tissue regeneration

IS Raja, C Kim, SJ Song, YC Shin, MS Kang, SH Hyon… - Nanomaterials, 2019 - mdpi.com
Owing to the astonishing properties of non-harmful viruses, tissue regeneration using virus-
based biomimetic materials has been an emerging trend recently. The selective peptide …

Panax notoginseng saponins provide neuroprotection by regulating NgR1/RhoA/ROCK2 pathway expression, in vitro and in vivo

X Shi, W Yu, T Yang, W Liu, Y Zhao, Y Sun… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Panax notoginseng saponins (PNS) extracted from a
traditional Chinese herbal medicine, Panax notoginseng (Burkill) FH Chen (Araliaceae) …

Tanshinone IIA promotes axonal regeneration in rats with focal cerebral ischemia through the inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC signaling

J Wang, G Ni, Y Liu, Y Han, L Jia… - … Design, Development and …, 2020 - Taylor & Francis
Purpose The aim of this study was to evaluate the neuroprotective effect of tanshinone IIA
(TSA) on focal cerebral ischemia in rats and to investigate whether it was associated with …

CRX haploinsufficiency compromises photoreceptor precursor translocation and differentiation in human retinal organoids

D Pan, X Zhang, K Jin, ZB Jin - Stem Cell Research & Therapy, 2023 - Springer
Background The CRX-associated autosomal dominant retinopathies suggest a possible
pathogenic mechanism of gene haploinsufficiency. However, based on reported human …

Decreased motor neuron support by SMA astrocytes due to diminished MCP1 secretion

JE Martin, TKT Nguyen, C Grunseich… - Journal of …, 2017 - Soc Neuroscience
Spinal muscular atrophy (SMA) is an autosomal-recessive disorder characterized by severe,
often fatal muscle weakness due to loss of motor neurons. SMA patients have deletions and …

A screened GPR1 peptide exerts antitumor effects on triple-negative breast cancer

C Huang, XY Dai, JX Cai, J Chen, BB Wang… - Molecular Therapy …, 2020 - cell.com
The adipokine chemerin has been considered an important regulator of tumor immune
surveillance. Chemerin recruits leukocytes through the receptor CMKLR1 to improve clinical …

Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA

CY Lin, CL Wu, KZ Lee, YJ Chen, PH Zhang… - Elife, 2019 - elifesciences.org
NogoA inhibits neurite outgrowth of motoneurons (NOM) through interaction with its
receptors, Nogo66/NgR. Inhibition of Nogo receptors rescues NOM, but not to the extent …

Morphoregulatory functions of the RNA-binding motif protein 3 in cell spreading, polarity and migration

J Pilotte, W Kiosses, SW Chan, HP Makarenkova… - Scientific Reports, 2018 - nature.com
RNA-binding proteins are emerging as key regulators of transitions in cell morphology. The
RNA-binding motif protein 3 (RBM3) is a cold-inducible RNA-binding protein with broadly …

Harnessing filamentous phages for enhanced stroke recovery

Y Li, K Yang, D Kong, X Li, H Duan, J Ye - Frontiers in Immunology, 2024 - frontiersin.org
Stroke poses a critical global health challenge, leading to substantial morbidity and
mortality. Existing treatments often miss vital timeframes and encounter limitations due to …