Results obtained from completed and on-going clinical studies indicate huge therapeutic
potential of stem cell-based therapy in the treatment of degenerative, autoimmune and …

It has been 15 years since the birth of human induced pluripotent stem cell (iPSC)
technology in 2007, and the scope of its application has been expanding. In addition to the …

The past 10 years have seen great advances in our ability to manipulate cell fate, including
the induction of pluripotency in vitro to generate induced pluripotent stem cells (iPSCs). This …

Accurate modeling of human neuronal cell biology has been a long‐standing challenge.
However, methods to differentiate human induced pluripotent stem cells (iPSCs) to neurons …

Human pluripotent stem cells (PSCs) are a promising source of cells for applications in
regenerative medicine. Directed differentiation of PSCs into specialized cells such as spinal …

To date, over 1800 gene therapy clinical trials have been completed, are ongoing or have
been approved worldwide. Our database brings together global information on gene therapy …

The field of stem-cell biology has been catapulted forward by the startling development of
reprogramming technology. The ability to restore pluripotency to somatic cells through the …

Transplantation of dopaminergic neurons can potentially improve the clinical outcome of
Parkinson's disease, a neurological disorder resulting from degeneration of mesencephalic …

Autologous transplantation of patient-specific induced pluripotent stem cell (iPSC)-derived
neurons is a potential clinical approach for treatment of neurological disease. Preclinical …

Ischemic stroke is a leading cause of death worldwide. A key secondary cell death
mechanism mediating neurological damage following the initial episode of ischemic stroke …