The cloning of genes encoding mammalian DNA binding transcription factors for RNA
polymerase II has provided the opportunity to analyze the structure and function of these …

▪ Abstract The past decade has seen an explosive increase in information about regulation
of eukaryotic gene transcription, especially for protein-coding genes. The most striking …

The general transcription factors of RNA polymerase II. Publisher Logo Genes &
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The entry of RNA polymerase II into a productive mode of elongation is controlled, in part, by
the postinitiation activity of positive transcription elongation factor b (P-TEFb)(Marshall, NF …

The largest subunit of mammalian RNA polymerase II (RNAP II) contains at its carboxyl
terminus an unusual domain consisting of 52 tandem repeats of the consensus sequence …

We report genetic and biochemical evidence that the RNA polymerase II carboxy-terminal
domain (CTD) lnteracts with a large multlsubunit complex that contains TATA-binding …

The 5′ half of the EWS gene has recently been described to be fused to the 3′ regions of
genes encoding the DNA-binding domain of several transcriptional regulators, including …

This review focuses on the gene-enzyme relationships and the regulation of different levels
of the aromatic amino acid biosynthetic pathway in a simple eukaryotic system, the …

Using DNA microarrays, we compared global transcript stability profiles following chemical
inhibition of transcription to rpb1-1 (a temperature-sensitive allele of yeast RNA polymerase …

The translocation (6; 9) is associated with a specific subtype of acute myeloid leukemia
(AML). Previously, it was found that breakpoints on chromosome 9 are clustered in one of …