Background: The connection between uric acid (UA) and renal impairment is well known
due to the urate capacity to precipitate within the tubules or extra-renal system. Emerging …

Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …

Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …

Purines perform many important functions in the cell, being the formation of the monomeric
precursors of nucleic acids DNA and RNA the most relevant one. Purines which also …

Zeolitic imidazolate frameworks (ZIFs) can be classified as metal–organic frameworks
(MOFs) or metal-azolate frameworks (MAFs) with unique topologies. The presence of five …

Malaria caused by the Plasmodium family of parasites, especially P. falciparum and P. vivax,
is a major health problem in many countries in the tropical and subtropical regions of the …

Purine metabolism in the circulatory system yields uric acid as its final oxidation product,
which is believed to be linked to the development of gout and kidney stones. Hyperuricemia …

Hyperuricemia, the physiological prerequisite for gout, is linked to the presence and severity
of multiple comorbidities that affect longevity and well-being. By using the baseline data from …

Aim Vascular endothelium plays a role in capillary transport of nutrients and drugs and
regulates angiogenesis, homeostasis, as well as vascular tone and permeability as a major …

Current evidences suggest that hyperuricemia is closely related to the overproduction or
underexcretion of uric acid (UA). Curcumin (CUR), a natural polyphenol component …