Abstract Background Three-dimensional (3D) culture of mesenchymal stem cells has
become an important research and development topic. However, comprehensive analysis of …

Dental stem cells (DSCs) are self-renewable cells that can be obtained easily from dental
tissues, and are a desirable source of autologous stem cells. The use of DSCs for stem cell …

Apical periodontitis is the inflammation and destruction of periradicular tissues, mediated by
microbial factors originating from the infected pulp space. This bacteria-mediated …

Microspheres applied in medical applications experience explosive development in recent
years, such as drug release, cell culture, and bone tissue engineering, etc. However, there …

Mesenchymal stem/stromal cell (MSC) spheroids generated in a three-dimensional (3D)
culture system serve as a surrogate model that maintain stem cell characteristics since these …

Mesenchymal stem cells (MSCs) show a decline in pluripotency and differentiation with
increased cell culture passages in 2D cultures. The 2D monolayer culture fails to correctly …

Craniofacial defects and dental tissue loss have significant negative impacts on the structure
and function of jaws and face, often resulting in psychological issues in patients …

Due to high proliferative capacity, multipotent differentiation, immunomodulatory abilities,
and lack of ethical concerns, dental pulp stem cells (DPSCs) are promising candidates for …

3D 细胞培养是一种模拟人体内细胞生长环境的体外培养方式, 使细胞保持原有的立体形态,
有利于细胞内基因的表达和信号转导. 3D 干细胞培养作为其中一个重要的研究方向 …

Methods and Results The hDPSCs were isolated and identified via flow cytometry. Targets
of miR-148a-3p were identified via bioinformatics and dual-luciferase reporter assay. After …