BRCA1-and BRCA2-associated hereditary breast and ovarian cancer (HBOC) is
characterized by an increased risk for female and male breast cancer, ovarian cancer …

As our understanding of the mechanisms of cancer treatment has increased, a growing
number of studies demonstrate pathways through which DNA damage repair (DDR) affects …

Pancreatic ductal adenocarcinoma (PDAC) has one of the highest incidence/death ratios
among all neoplasms due to its late diagnosis and dominant chemoresistance. Most PDAC …

Background Chemoresistance of pancreatic cancer is the main reason for the poor treatment
effect of pancreatic cancer patients. Exploring chemotherapy resistance-related genes has …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive tumor and is associated
with a poor prognosis. Treatment strategies for PDAC are largely ineffective primarily …

In recent years, a growing number of studies have evaluated the role of exosomes in
pancreatic ductal adenocarcinoma cancer (PDAC) demonstrating their involvement in a …

Pancreatic cancer (PC) is the seventh leading cause of cancer-related death. PC incidence
has continued to increase by about 1% each year in both men and women. Although the 5 …

Pancreatic adenocarcinoma is by far the deadliest type of cancer. Inflammation is one of the
important risk factors in tumor development. However, it is not yet clear whether deterioration …

Abstract Objectives Transcriptional classifiers (Bailey, Moffitt and Collison) are key
prognostic factors of pancreatic ductal adenocarcinoma (PDAC). Among these classifiers …

Radiotherapy (RT) has been widely used in the clinical treatment of cancers, but
radiotherapy resistance (RR) leads to RT failure, tumor recurrence and metastasis. Many …