[HTML][HTML] Cell death due to electroporation–a review

TB Napotnik, T Polajžer, D Miklavčič - Bioelectrochemistry, 2021 - Elsevier
Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

Membrane electroporation and electropermeabilization: mechanisms and models

T Kotnik, L Rems, M Tarek… - Annual review of …, 2019 - annualreviews.org
Exposure of biological cells to high-voltage, short-duration electric pulses causes a transient
increase in their plasma membrane permeability, allowing transmembrane transport of …

[HTML][HTML] Effects of high voltage nanosecond electric pulses on eukaryotic cells (in vitro): A systematic review

TB Napotnik, M Reberšek, PT Vernier, B Mali… - …, 2016 - Elsevier
For this systematic review, 203 published reports on effects of electroporation using
nanosecond high-voltage electric pulses (nsEP) on eukaryotic cells (human, animal, plant) …

Induction of cell death mechanisms and apoptosis by nanosecond pulsed electric fields (nsPEFs)

SJ Beebe, NM Sain, W Ren - Cells, 2013 - mdpi.com
Pulse power technology using nanosecond pulsed electric fields (nsPEFs) offers a new
stimulus to modulate cell functions or induce cell death for cancer cell ablation. New data …

[HTML][HTML] Revisiting the role of pulsed electric fields in overcoming the barriers to in vivo gene electrotransfer

S Sachdev, T Potočnik, L Rems, D Miklavčič - Bioelectrochemistry, 2022 - Elsevier
Gene therapies are revolutionizing medicine by providing a way to cure hitherto incurable
diseases. The scientific and technological advances have enabled the first gene therapies to …

Cell electrofusion using nanosecond electric pulses

L Rems, M Ušaj, M Kandušer, M Reberšek… - Scientific reports, 2013 - nature.com
Electrofusion is an efficient method for fusing cells using short-duration high-voltage electric
pulses. However, electrofusion yields are very low when fusion partner cells differ …

In-vitro bipolar nano-and microsecond electro-pulse bursts for irreversible electroporation therapies

MB Sano, CB Arena, MR DeWitt, D Saur, RV Davalos - Bioelectrochemistry, 2014 - Elsevier
Under the influence of external electric fields, cells experience a rapid potential buildup
across the cell membrane. Above a critical threshold of electric field strength, permanent cell …

Cytoskeletal disruption after electroporation and its significance to pulsed electric field therapies

PM Graybill, RV Davalos - Cancers, 2020 - mdpi.com
Pulsed electric fields (PEFs) have become clinically important through the success of
Irreversible Electroporation (IRE), Electrochemotherapy (ECT), and nanosecond PEFs …

Single-site sonoporation disrupts actin cytoskeleton organization

X Chen, RS Leow, Y Hu… - Journal of The Royal …, 2014 - royalsocietypublishing.org
Sonoporation is based upon an ultrasound–microbubble cavitation routine that physically
punctures the plasma membrane on a transient basis. During such a process, the actin …

Modifications of plasma membrane organization in cancer cells for targeted therapy

A Choromańska, A Chwiłkowska, J Kulbacka… - Molecules, 2021 - mdpi.com
Modifications of the composition or organization of the cancer cell membrane seem to be a
promising targeted therapy. This approach can significantly enhance drug uptake or …